Evidence map›Paper›PMID 40870447›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Nasal Irrigations: A 360-Degree View in Clinical Practice.

Luca Pecoraro, Elisabetta Di Muri, Gianluca Lezzi, Silvia Picciolo, Marta De Musso, Michele Piazza, Mariangela Bosoni, Flavia Indrio

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Olfactory Decline in Elderly at High Altitudes: A Narrative Review.International journal of general medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luca PecoraroPediatric Unit, Ospedale Vito Fazzi, ASL Lecce, 73100 Lecce, Italy.ORCID 0000-0002-9765-8006
Elisabetta Di MuriPediatric Unit, Ospedale Vito Fazzi, ASL Lecce, 73100 Lecce, Italy.
Gianluca LezziPediatric Unit, Ospedale Vito Fazzi, ASL Lecce, 73100 Lecce, Italy.
Silvia PiccioloPediatric Department, University of Bari Aldo Moro, 70121 Bari, Italy.
Marta De MussoPediatric Department, University of Bari Aldo Moro, 70121 Bari, Italy.
Michele PiazzaPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37129 Verona, Italy.ORCID 0000-0001-7746-8267
Mariangela BosoniPrivate Practice Pediatric Allergist, 20100 Milan, Italy.
Flavia IndrioDepartment of Experimental Medicine Pediatric Section, University of Salento Hospital "Vito Fazzi", 73100 Lecce, Italy.ORCID 0000-0001-9789-7878

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasal irrigation (NI) is an effective, safe, low-cost strategy for treating and preventing upper respiratory tract diseases. High-volume, low-pressure saline irrigations are the most efficient method for removing infectious agents, allergens, and inflammatory mediators. This article reviews clinical evidence supporting NI use in various conditions: nasal congestion in infants, recurrent respiratory infections, acute and chronic rhinosinusitis, allergic and gestational rhinitis, empty nose syndrome, and post-endoscopic sinus surgery care. NI improves symptoms, reduces recurrence, enhances the efficacy of topical drugs, and decreases the need for antibiotics and decongestants. During the COVID-19 pandemic, NI has also been explored as a complementary measure to reduce viral load. Due to the safe profile and mechanical cleansing action on inflammatory mucus, nasal irrigations represent a valuable adjunctive treatment across a wide range of sinonasal conditions.

Indexed as

Nasal LavageCOVID-19HumansRespiratory Tract InfectionsRhinitisSARS-CoV-2Sinusitismechanical cleansingnasal irrigationsinonasal disordersupper respiratory tract infectionsviral load reduction

Identifiers

PMID40870447
PMCPMC12388252

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.