Evidence map›Paper›PMID 40870422›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Current Narrative Review-Application of Blood Flow Restriction Exercise in Clinical Knee Problems.

Saehim Kwon, Ki-Cheor Bae, Chang-Jin Yon, Du-Han Kim

Registry-linked trialAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07384780 (Isokinetic Exercise Combined With Blood Flow Restriction), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07384780 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Isokinetic Exercise Combined With Blood Flow Restriction: High-Load Vs Low-Load Training : A Randomized Controlled Trial in Post-ACL Reconstruction Populations

TypeinterventionalSponsorGulf Medical UniversityRan2026 to 2026Enrolled60ConditionsACL Reconstruction, ACL RepairArmsHigh Load Isokinetic Training with Blood Flow Restriction, Low Load Isokinetic Training with Blood Flow Restriction
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saehim KwonDepartment of Orthopaedic Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.ORCID 0000-0002-5774-8250
Ki-Cheor BaeDepartment of Orthopedic Surgery, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Chang-Jin YonDepartment of Orthopedic Surgery, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.ORCID 0000-0003-3580-4175
Du-Han KimDepartment of Orthopedic Surgery, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.ORCID 0000-0002-6636-9340

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quadricep weakness is frequently observed in patients following anterior cruciate ligament (ACL) injury or in those with knee osteoarthritis, often contributing to functional impairments and persistent symptoms. While high-intensity resistance training has been shown to effectively improve muscle strength, its application may be limited in certain populations due to pain or the risk of surgical complications. In recent years, blood flow restriction (BFR) training has emerged as a promising alternative. Growing evidence indicates that low-load BFR exercise can significantly improve muscle strength, induce hypertrophy, and enhance knee function, with outcomes comparable to those of high-intensity resistance training. When implemented using appropriate protocols, BFR training appears to be a safe and efficacious rehabilitation strategy for individuals with knee pathology.

Indexed as

Blood Flow Restriction TherapyExercise TherapyKnee JointAnterior Cruciate Ligament InjuriesHumansMuscle StrengthOsteoarthritis, KneeResistance Traininganterior cruciate ligament reconstructionblood flow restrictionexerciseknee osteoarthritisquadriceps muscle

Identifiers

PMID40870422
PMCPMC12387686

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.