Riboflavin as a Dual-Function Additive for Enhancing Biodegradation in Piezoelectric PLA/BT Composites.

Natalia Puszczykowska, Piotr Rytlewski, Agnieszka Mirkowska, Paweł Cyprys, Piotr Augustyn, Kacper Fiedurek

Abstract read

In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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5 · Who and what money

Authors and funding

6 authors.

Natalia PuszczykowskaFaculty of Materials Engineering, Kazimierz Wielki University, Chodkiewicza 30, 85-064 Bydgoszcz, Poland.ORCID 0000-0002-5184-6052

Piotr RytlewskiFaculty of Materials Engineering, Kazimierz Wielki University, Chodkiewicza 30, 85-064 Bydgoszcz, Poland.

Agnieszka MirkowskaFaculty of Electrical Engineering, Wroclaw University of Science and Technology, pl. Grunwaldzki 13, 50-377 Wroclaw, Poland.ORCID 0000-0001-6713-1927

Paweł CyprysFaculty of Mechatronics, Kazimierz Wielki University, Kopernika 1, 85-074 Bydgoszcz, Poland.

Piotr AugustynFaculty of Materials Engineering, Kazimierz Wielki University, Chodkiewicza 30, 85-064 Bydgoszcz, Poland.ORCID 0000-0002-0752-3010

Kacper FiedurekFaculty of Mechatronics, Kazimierz Wielki University, Kopernika 1, 85-074 Bydgoszcz, Poland.

Funding

Polish Minister of Science "Regional Initiative of Excellence" No.: RID/SP/0048/2024/01.

6 · The paper itself

Abstract

Poly(lactic acid)/barium titanate (PLA/BT) composites exhibit piezoelectric properties desirable for bone tissue engineering, but their low biodegradability limits implant resorption. In this study, riboflavin (RF) is introduced as a dual-function additive that enhances biodegradation in PLA/BT composites. Its addition led to significantly increased microbial colonization and a five-fold higher mass loss compared to unmodified samples. These observations are consistent with the known polarity of RF and its role as a cofactor in microbial metabolism. The PLA/BT/RF composites are subjected to full characterization, including thermogravimetric analysis (TG), differential scanning calorimetry (DSC), tensile testing, dynamic mechanical analysis (DMA), dielectric permittivity measurements, and determination of piezoelectric coefficient d

Indexed as

BaTiO3biodegradationpiezoelectric biomaterialspiezoelectric compositesPLAriboflavin

Identifiers

PMID40870181

DOI10.3390/ma18163860

PMCPMC12387822

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.