Evidence map›Paper›PMID 40870019›Full record

ArticleGenes2025

Association Between UGT1A1 mRNA Expression and Cis-Acting Genetic Variants and Trans-Acting Transcriptional Regulators in Human Liver Samples.

Matthew J Taylor, Joseph M Collins, Abelardo D Montalvo, Danxin Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The Impact ofGenes · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew J TaylorDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL 32610, USA.
Joseph M CollinsDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL 32610, USA.
Abelardo D MontalvoDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-4314-1295
Danxin WangDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-7134-3065

Funding

Expression genetics of pharmacogenesR35GM140845 · NIGMS · UNIVERSITY OF FLORIDA · PI Danxin Wang · 2021 to 2026
$2.2M
NIGMS NIH HHS R35 GM140845NIH HHS 1R35GM140845-25
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GlucuronosyltransferaseLiverPolymorphism, Single NucleotideAdultBlack or African AmericanFemaleHumansMaleMiddle AgedPromoter Regions, GeneticRNA, MessengerUGT1A1 EnzymeWhiteGlucuronosyltransferaseRNA, MessengerUGT1A1 Enzymeancestry differencesgene expressiongenetic polymorphismspersonalized medicineUGT1A1

Identifiers

PMID40870019
PMCPMC12385207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.