Evidence map›Paper›PMID 40869974›Full record

Observational studyGenes2025

Unveiling the Spectrum: Clinical and Molecular Insights from a Spanish Pediatric Cohort with Hypermobility Disorders and Ehlers-Danlos Syndrome.

David Foz Felipe, Dídac Casas-Alba, Sara H Sadok, Marina Toral Fernández, Lourdes Vega-Hanna, Laura Plaza, Asunción Vicente Villa, Judith Armstrong, Encarna Guillén-Navarro, Antonio F Martínez-Monseny

Abstract readObservational Study
In one paragraph

Observational study in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David Foz FelipePediatrics Department, Hospital Sant Joan de Déu, 08950 Barcelona, Spain.
Dídac Casas-AlbaDepartment of Medical Genetics, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, 08950 Barcelona, Spain.ORCID 0000-0001-5659-9188
Sara H SadokDepartment of Medical Genetics, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, 08950 Barcelona, Spain.
Marina Toral FernándezPediatrics Department, Hospital Sant Joan de Déu, 08950 Barcelona, Spain.
Lourdes Vega-HannaDepartment of Genetics, Hospital Santa Creu i Sant Pau, 08950 Barcelona, Spain.
Laura PlazaPediatrics Department, Hospital Sant Joan de Déu, 08950 Barcelona, Spain.
Asunción Vicente VillaDepartment of Dermatology, Hospital Sant Joan de Déu, 08950 Barcelona, Spain.
Judith ArmstrongGenomic Unit, Department of Genetic and Molecular Medicine, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, 08950 Barcelona, Spain.ORCID 0000-0003-0588-9307
Encarna Guillén-NavarroDepartment of Medical Genetics, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, 08950 Barcelona, Spain.
Antonio F Martínez-MonsenyDepartment of Medical Genetics, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, 08950 Barcelona, Spain.ORCID 0000-0002-0960-3153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosing hypermobility disorders and Ehlers-Danlos syndrome (EDS) in children is challenging due to overlapping features with generalized joint hypermobility (GJH) and the lack of biomarkers.

Indexed as

Ehlers-Danlos SyndromeJoint InstabilityAdolescentChildChild, PreschoolCohort StudiesFemaleHumansMaleSpaincollagenopathyEhlers-Danlos syndromehypermobility spectrum disordersjoint hypermobilitypediatrics

Identifiers

PMID40869974
PMCPMC12386060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.