Genomic Alterations and Microbiota Crosstalk in Hepatic Cancers: The Gut-Liver Axis in Tumorigenesis and Therapy.

Yuanji Fu, Jenny Bonifacio-Mundaca, Christophe Desterke, Íñigo Casafont, Jorge Mata-Garrido

Abstract readReview

In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Molecular classification and construction of prognostic risk model via machine learning based on metabolic-related genes in hepatocellular carcinoma.Translational cancer research · 2026
Article
From dysbiosis to malignancy: decoding gut-driven pathways to clinical management in hepatocellular carcinoma.Frontiers in cellular and infection microbiology · 2026
Review
Microbial dysbiosis in cholangiocarcinoma.Frontiers in microbiology · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuanji FuInstitut Necker Enfants Malades, INSERM, CNRS, Université Paris Cité, F-75015 Paris, France.ORCID 0000-0002-2226-8230

Jenny Bonifacio-MundacaNational Tumor Bank, Department of Pathology, National Institute of Neoplastic Diseases, Surquillo 15038, Peru.ORCID 0000-0002-0798-7544

Christophe DesterkeFaculté de Médecine du Kremlin Bicêtre, University Paris-Sud, Université Paris-Saclay, 94270 Le Kremlin-Bicêtre, France.

Íñigo CasafontCell and Tissue Biology Group, Anatomy and Cell Biology Department, University of Cantabria-IDIVAL, 39011 Santander, Spain.ORCID 0000-0001-5691-6841

Jorge Mata-GarridoCell and Tissue Biology Group, Anatomy and Cell Biology Department, University of Cantabria-IDIVAL, 39011 Santander, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarcinogenesisCarcinoma, HepatocellularCholangiocarcinomaGastrointestinal MicrobiomeLiver NeoplasmsAnimalsEpigenesis, GeneticHumansLiverMutationcancergut–liver axishepatocellular carcinomaintrahepatic cholangiocarcinomamicrobiota

Identifiers

PMID40869967

DOI10.3390/genes16080920

PMCPMC12385877

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.