Evidence map›Paper›PMID 40869954›Full record

ArticleGenes2025

Genetic Factors of Elite Wrestling Status: A Multi-Ethnic Comparative Study.

Ayumu Kozuma, Celal Bulgay, Hirofumi Zempo, Mika Saito, Minoru Deguchi, Hiroki Homma, Shingo Matsumoto, Ryutaro Matsumoto, Anıl Kasakolu, Hasan H Kazan and 13 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Ayumu KozumaGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.
Celal BulgaySports Science Faculty, Bingöl University, Bingöl 12000, Türkiye.ORCID 0000-0003-4026-9883
Hirofumi ZempoFaculty of Health and Nutrition, Tokyo Seiei College, Tokyo 124-8530, Japan.ORCID 0000-0003-2248-8580
Mika SaitoGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.
Minoru DeguchiFaculty of Health Sciences, Kyorin University, Tokyo 192-8508, Japan.
Hiroki HommaGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.
Shingo MatsumotoGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.
Ryutaro MatsumotoFaculty of Education, Ikuei University, Gumma 370-0011, Japan.
Anıl KasakoluGraduate School of Natural and Applied Sciences, Ankara University, Ankara 06135, Türkiye.
Hasan H KazanDepartment of Medical Biology, Gulhane Faculty of Medicine, University of Health Sciences, Ankara 06010, Türkiye.ORCID 0000-0001-7936-8606
Türker BıyıklıSports Science Faculty, Marmara University, İstanbul 34722, Türkiye.
Seyrani KoncagülDepartment of Animal Science, Faculty of Agriculture, Ankara University, Ankara 06135, Türkiye.
Giyasettin BaydaşDepartment of Physiology, Faculty of Medicine, İstanbul Medeniyet University, İstanbul 34700, Türkiye.
Mehmet A ErgunDepartment of Medical Genetics, Faculty of Medicine, Gaz University, Ankara 06560, Türkiye.ORCID 0000-0001-9696-0433
Attila SzaboFaculty of Health and Sport Sciences, Széchenyi István University, H-9026 Győr, Hungary.ORCID 0000-0003-2788-4304
Ekaterina A SemenovaDepartment of Molecular Biology and Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0003-1248-2855
Andrey K LarinDepartment of Molecular Biology and Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-9429-792X
Nikolay A KuleminDepartment of Molecular Biology and Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Edward V GenerozovDepartment of Molecular Biology and Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-6314-4883
Takanobu OkamotoGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.
Koichi NakazatoGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.ORCID 0000-0002-2479-5771
Ildus I AhmetovDepartment of Molecular Biology and Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-6335-4020
Naoki KikuchiGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.ORCID 0000-0001-5901-7307

Funding

Gazi University Rectorate TCD-2023-8868the programme Grants in-Aid for Scientific Research 19K11531
6 · The paper itself

Abstract

backgroundIn recent years, comprehensive analyses using a genome-wide association study (GWAS) have been conducted to identify genetic factors related to athletic performance. In this study, we investigated the association between genetic variants and elite wrestling status across multiple ethnic groups using a genome-wide genotyping approach.

methodsThis study included 168 elite wrestlers (64 Japanese, 67 Turkish, and 36 Russian), all of whom had competed in international tournaments, including the Olympic Games. Control groups consisted of 306 Japanese, 137 Turkish, and 173 Russian individuals without elite athletic backgrounds. We performed a GWAS comparing allele frequencies of single-nucleotide polymorphisms (SNPs) between elite wrestlers and controls in each ethnic cohort. Cross-population analysis comprised (1) identifying SNPs with nominal significance (

resultsThe GWAS identified 328,388 (Japanese), 23,932 (Turkish), and 30,385 (Russian) SNPs reaching nominal significance. Meta-analysis revealed that the

conclusionsThis is the first study to investigate gene polymorphisms associated with elite wrestling status in a multi-ethnic cohort.

Indexed as

Athletic PerformanceEthnicityPolymorphism, Single NucleotideWrestlingAdultAthletesGene FrequencyGenome-Wide Association StudyHumansMaleMuscle, SkeletalTurkeyYoung Adultathlete statuscomprehensive analysisgene expressiongenome-wide association studygenotypeskeletal muscletalent

Identifiers

PMID40869954
PMCPMC12385711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.