Evidence map›Paper›PMID 40869940›Full record

ArticleGenes2025

Autophagy and PXR Crosstalk in the Regulation of Cancer Drug Metabolism and Resistance According to Gene Mutational Status in Colorectal Cancer.

Evangelos Koustas, Panagiotis Sarantis, Eleni-Myrto Trifylli, Eleftheria Dikoglou-Tzanetatou, Evangelia Ioakeimidou, Ioanna A Anastasiou, Michalis V Karamouzis, Stamatios Theocharis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evangelos KoustasOncology Department, General Hospital Evangelismos, Ipsilantou 45-47, 106 76 Athens, Greece.
Panagiotis SarantisFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, Greece.ORCID 0000-0001-5848-7905
Eleni-Myrto TrifylliGI-Liver Unit, 2nd Department of Internal Medicine, National and Kapodistrian University of Athens, General Hospital of Athens "Hippocratio", 114 Vas Sofias, 115 27 Athens, Greece.ORCID 0000-0002-0080-9032
Eleftheria Dikoglou-TzanetatouFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Evangelia IoakeimidouFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Ioanna A AnastasiouDiabetes Center, First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 115 27 Athens, Greece.ORCID 0000-0002-7560-0575
Michalis V KaramouzisUniversity Pathology Clinic, General and Oncology Hospital "Agioi Anargyroi", National and Kapoditrian University of Athens, Timiou Stavrou 14, 145 64 Kifisia, Greece.ORCID 0000-0003-1369-8201
Stamatios TheocharisFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutophagyColorectal NeoplasmsDrug Resistance, NeoplasmPregnane X ReceptorAntineoplastic AgentsApoptosisCell Line, TumorGene Expression Regulation, NeoplasticHumansIrinotecanMutationSignal TransductionAntineoplastic AgentsIrinotecanPregnane X Receptorautophagycolorectal canceririnotecanpregnane X receptor—PXR

Identifiers

PMID40869940
PMCPMC12385266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.