Evidence map›Paper›PMID 40869599›Full record

ReviewJournal of clinical medicine2025

Flexible Bronchoscopy and Non-Small-Cell Lung Cancer Staging: A Narrative Review of Modern Techniques for Optimized Clinical Decision-Making.

Simona-Maria Roșu, Denisa Maria Mitroi, Oana Maria Catană, Viorel Biciușcă, Sorina Ionelia Stan, Beatrice Mahler, Oana-Andreea Parliteanu, Adina Andreea Mirea, Mara Amalia Bălteanu

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simona-Maria RoșuDoctoral School, University of Medicine and Pharmacy, 200349 Craiova, Romania.
Denisa Maria MitroiDoctoral School, University of Medicine and Pharmacy, 200349 Craiova, Romania.
Oana Maria CatanăDoctoral School, University of Medicine and Pharmacy, 200349 Craiova, Romania.ORCID 0009-0000-9976-2256
Viorel BiciușcăDepartment of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-9451-6969
Sorina Ionelia StanDepartment of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Beatrice MahlerDepartment of Pneumology, "Marius Nasta" Institute for Pneumology, 050159 Bucharest, Romania.ORCID 0000-0002-9240-922X
Oana-Andreea ParliteanuDepartment of Pathophysiology, Faculty of Medicine, "Titu Maiorescu" University, 040051 Bucharest, Romania.
Adina Andreea MireaDepartment of Oral-Dental Prevention, University of Medicine and Pharmacy, 200349 Craiova, Romania.ORCID 0009-0001-4039-0811
Mara Amalia BălteanuDepartment of Pneumology, "Marius Nasta" Institute for Pneumology, 050159 Bucharest, Romania.ORCID 0009-0004-8409-5904

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small-cell lung cancer (NSCLC) is a widespread and aggressive form of cancer, and in cases of its occurrence, accurate diagnosis and precise staging play a crucial role in determining treatment and estimating prognosis. Flexible bronchoscopy (FB) is a minimally invasive method used to assess the local and regional extent of the disease. FB facilitates the identification of endobronchial lesions and the collection of biopsy samples for histopathological diagnosis. It also enables the evaluation of regional lymph node involvement via advanced techniques such as endobronchial ultrasound with fine-needle aspiration (EBUS-TBNA). This method has high sensitivity and specificity, reducing the need for more invasive interventions like mediastinoscopy. The integration of endobronchial ultrasound (EBUS) has revolutionized NSCLC staging by providing detailed images and guiding biopsies of suspicious lymph nodes. Additionally, FB is valuable in staging the extent of primary tumor growth, providing critical information about the invasion of adjacent structures. In conclusion, FB, supported by advanced technologies, is important for the staging of NSCLC, improving medical practice and patient prognosis.

Indexed as

diagnosisEBUS-TBNAflexible bronchoscopynon-small-cell lung cancerstaging

Identifiers

PMID40869599
PMCPMC12386715

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.