Evidence map›Paper›PMID 40869489›Full record

ReviewJournal of clinical medicine2025

Efficacy and Safety of Esaxerenone for Essential Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Abdelrahman Hafez, Ahmed Abdelaziz, Ahmed Mansour, Ibrahim Kamal, Ali Bakr, Ahmed Farid Gadelmawla, Hanaa Elsayed, Mohamed Reyad Mohamed, Karim Ali, Mohamed Elhelw

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Low-Dose Triple-Pill of Telmisartan, Amlodipine, and Indapamide for Initial Hypertension Treatment: A GRADE-Assessed Meta-analysis of Randomized Trials.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdelrahman HafezMedical Research Group of Egypt (MRGE), Negida Academy, Arlington, MA 02474, USA.ORCID 0000-0003-1972-3885
Ahmed AbdelazizMedical Research Group of Egypt (MRGE), Negida Academy, Arlington, MA 02474, USA.ORCID 0000-0002-1257-3450
Ahmed MansourMedical Research Group of Egypt (MRGE), Negida Academy, Arlington, MA 02474, USA.ORCID 0009-0008-8938-5723
Ibrahim KamalMedical Research Group of Egypt (MRGE), Negida Academy, Arlington, MA 02474, USA.
Ali BakrMedical Research Group of Egypt (MRGE), Negida Academy, Arlington, MA 02474, USA.ORCID 0009-0001-4470-0012
Ahmed Farid GadelmawlaMedical Research Group of Egypt (MRGE), Negida Academy, Arlington, MA 02474, USA.ORCID 0000-0002-5802-2291
Hanaa ElsayedMedical Research Group of Egypt (MRGE), Negida Academy, Arlington, MA 02474, USA.ORCID 0000-0002-7886-7435
Mohamed Reyad MohamedCardiology Department, Banner University Medical Center, Phoenix, AZ 85006, USA.
Karim AliDepartment of Internal Medicine, Hennepin County Medical Center, Minneapolis, MN 55415, USA.ORCID 0000-0003-4318-8843
Mohamed ElhelwDepartment of Internal Medicine, University of Kentucky Healthcare, University of Kentucky, KY 40536, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

esaxerenoneessential hypertensionHTN usual caremeta-analysis

Identifiers

PMID40869489
PMCPMC12386546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.