Evidence map›Paper›PMID 40869374›Full record

ArticleInternational journal of molecular sciences2025

The Influence of Genetic Polymorphisms and Psychosocial Determinants on Suicidal Behaviors: A Case-Control Study of

Mihaela Elvira Cîmpianu, Emilian Onișan, Viviana Maria Sărac, Ioan Sărac, Mariana Ganea, Gligor Octavia, Ștefana Bâlici, Gheorghe Zsolt Nicula, Elena Maria Domșa, Teodora Cîmpianu and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mihaela Elvira CîmpianuDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-1647-9381
Emilian OnișanGenetic Department, University of Life Sciences "King Mihai I" from Timisoara, 300645 Timisoara, Romania.ORCID 0009-0003-6288-8738
Viviana Maria SăracFaculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.
Ioan SăracGenetic Department, University of Life Sciences "King Mihai I" from Timisoara, 300645 Timisoara, Romania.
Mariana GaneaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 29 Nicolae Jiga Street, 410028 Oradea, Romania.ORCID 0000-0003-4643-2151
Gligor OctaviaDepartment of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 10, 1 December Square, 410073 Oradea, Romania.
Ștefana BâliciDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Gheorghe Zsolt NiculaDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Elena Maria DomșaDepartment of Social Sciences, "1st December 1918" University of Alba Iulia, 510009 Alba Iulia, Romania.
Teodora CîmpianuFaculty of Medicine, Iuliu Haṭieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.
Sergiu Ionica RusuFaculty of Sociology and Social Work, "Babeș-Bolyai" University, 400084 Cluj-Napoca, Romania.
Horia George ComanDepartment of Medical Psychology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Mihaela Laura Vică MateiDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.ORCID 0000-0003-0811-0821
Costel Vasile SisermanLegal Medicine Institute, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-6124-8582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Suicide, a major contributor to global mortality rates, especially among young patients, remains insufficiently integrated into public health initiatives despite notable progress in identifying its determinants. The prediction of suicidal behavior remains complex, often relying on subjective assessments rather than objective biomarkers. Single nucleotide polymorphisms (SNPs) such as rs110402 (

Indexed as

Polymorphism, Single NucleotideReceptors, Corticotropin-Releasing HormoneReceptor, trkBSuicideTacrolimus Binding ProteinsAdultAllelesCase-Control StudiesCRF Receptor, Type 1FemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMembrane GlycoproteinsMiddle AgedCRF Receptor, Type 1CRHR1 protein, humanMembrane GlycoproteinsReceptors, Corticotropin-Releasing HormoneReceptor, trkBTacrolimus Binding Protein 5Tacrolimus Binding Proteinstropomyosin-related kinase-B, humanbiomarkerspsychosocial determinantssingle nucleotide polymorphisms (SNPs)suicidal behaviorsuicide prevention

Identifiers

PMID40869374
PMCPMC12386593

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.