Evidence map›Paper›PMID 40869349›Full record

ArticleInternational journal of molecular sciences2025

Circulating Calprotectin Distinguishes Metastatic Melanoma and Predicts Liver Metastasis.

István Szász, Viktória Koroknai, Tünde Várvölgyi, Gabriella Emri, Imre Lőrinc Szabó, Margit Balázs

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

István SzászHUN-REN-UD Public Health Research Group, Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4028 Debrecen, Hungary.
Viktória KoroknaiDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4028 Debrecen, Hungary.
Tünde VárvölgyiDepartment of Dermatology, Faculty of Medicine, University of Debrecen, 4028 Debrecen, Hungary.
Gabriella EmriDepartment of Dermatology, Faculty of Medicine, University of Debrecen, 4028 Debrecen, Hungary.ORCID 0000-0002-2877-4740
Imre Lőrinc SzabóDepartment of Dermatology, Faculty of Medicine, University of Debrecen, 4028 Debrecen, Hungary.ORCID 0000-0002-9628-4372
Margit BalázsHUN-REN-UD Public Health Research Group, Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4028 Debrecen, Hungary.ORCID 0000-0002-4246-2321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calprotectin, a heterodimer of the S100A8 and S100A9 proteins, has been implicated in cancer-related inflammation and metastasis. Its role in melanoma progression, particularly in organ-specific metastasis, remains underexplored. In this retrospective study, plasma calprotectin levels were measured in 201 individuals, including healthy controls (

Indexed as

Biomarkers, TumorLeukocyte L1 Antigen ComplexLiver NeoplasmsMelanomaAdultAgedFemaleHumansL-Lactate DehydrogenaseMaleMiddle AgedPrognosisRetrospective StudiesROC CurveS100 Calcium Binding Protein beta SubunitBiomarkers, TumorLeukocyte L1 Antigen ComplexL-Lactate DehydrogenaseS100 Calcium Binding Protein beta Subunitbiomarkercalprotectinliquid biopsyliver metastasismelanomaorgan specific metastasisS100B and LDH

Identifiers

PMID40869349
PMCPMC12386951

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.