Evidence map›Paper›PMID 40869343›Full record

ArticleInternational journal of molecular sciences2025

Clonal Hematopoiesis and Outcomes After High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Patients with AML, Myeloma, and Lymphoma.

Corinne Natalie Schmid, Katharina Sponagel, Ulrike Bacher, Katja Seipel, Naomi Porret, Gertrud Wiedemann, Michèle Hoffmann, Michael Daskalakis, Thomas Pabst

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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Low-FrequencyCancers · 2026
    Article
  3. Influence ofBiomedicines · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Corinne Natalie SchmidDepartment of Medical Oncology, Inselspital, University Hospital of Bern, 3010 Bern, Switzerland.
Katharina SponagelDepartment of Medical Oncology, Inselspital, University Hospital of Bern, 3010 Bern, Switzerland.
Ulrike BacherDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-8771-947X
Katja SeipelDepartment for BioMedical Research, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-3128-1573
Naomi PorretDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-2515-1935
Gertrud WiedemannDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-2259-1011
Michèle HoffmannDepartment of Medical Oncology, Inselspital, University Hospital of Bern, 3010 Bern, Switzerland.
Michael DaskalakisDepartment of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-8138-0505
Thomas PabstDepartment of Medical Oncology, Inselspital, University Hospital of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-6055-5257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous stem cell transplantation (ASCT) after high-dose chemo-therapy (HDCT) is an option of consolidation therapy in patients with AML, lymphoma, or myeloma. Clonal hematopoiesis (CH) is a premalignant state, associated with an increased risk of hematological cancer. The incidence of CH in patients with AML, myeloma, and lymphoma and its effect on the outcome after HDCT/ASCT remain poorly studied. Here we screened 142 patients treated with HDCT/ASCT between 2002 and 2021 at Bern University Hospital for somatic gene mutations in

Indexed as

Clonal HematopoiesisHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteLymphomaMultiple MyelomaAdultAgedFemaleHumansMaleMiddle AgedMutationTransplantation, AutologousTreatment Outcomeacute myeloid leukemia (AML)autologous stem cell transplantation (ASCT)clonal hematopoiesis (CH)high-dose chemotherapy (HDCT)lymphomamyeloma

Identifiers

PMID40869343
PMCPMC12386481

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.