Evidence map›Paper›PMID 40869340›Full record

ArticleInternational journal of molecular sciences2025

Preparturient Oral Selenitetriglycerides Supplementation Elevates Erythrocyte Glutathione Peroxidase Activity and Modulates Hepatic

Katarzyna Żarczyńska, Katarzyna Różańska, Paweł Brym, Dawid Tobolski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katarzyna ŻarczyńskaDepartment and Clinic of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0003-4969-8887
Katarzyna RóżańskaDepartment and Clinic of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
Paweł BrymDepartment of Animal Genetics, Faculty of Animal Bioengineering, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-1896-7610
Dawid TobolskiDepartment of Large Animal Diseases and Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.ORCID 0000-0002-2925-4165

Funding

Funded by the KNOW (Leading National Research Centre) Scientific Consortium "Healthy Animal - Safe Food", under Ministry of Science and Higher Education decision No. 05-1/KNOW2/2015, Publication of this article was funded by the Minister of Science under 05-1/KNOW2/2015
6 · The paper itself

Abstract

The transition period in dairy cows, spanning late pregnancy and early lactation, is associated with substantial metabolic and immunological challenges, leading to increased oxidative stress and inflammation. Selenium (Se), particularly in organic forms, supports antioxidant defenses, immune function, and metabolic regulation. This study investigated the effects of supplementing periparturient Holstein-Friesian cows with orally administered selenitetriglycerides (0.5 mg Se/kg body weight/day starting 12 days before the expected calving date and continuing until parturition) on antioxidant enzyme activity and on the hepatic expression of key inflammatory and metabolic genes. Serum selenium concentrations and erythrocyte glutathione peroxidase (GSH-Px) activity were assessed before and after parturition, and hepatic gene expression levels of tumor necrosis factor alpha (

Indexed as

ErythrocytesGlutathione PeroxidaseLiverPPAR alphaPPAR deltaTriglyceridesTumor Necrosis Factor-alphaAdministration, OralAnimalsAntioxidantsCattleDietary SupplementsFemaleLactationPostpartum PeriodPregnancyAntioxidantsGlutathione PeroxidasePPAR alphaPPAR deltaRNA, MessengerSeleniumTriglyceridesTumor Necrosis Factor-alphaantioxidant enzymesHolstein–Friesian cowsinflammationmetabolic regulationperiparturient healthselenitetriglyceridesselenium supplementationtransition period

Identifiers

PMID40869340
PMCPMC12386483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.