Evidence map›Paper›PMID 40869335›Full record

ArticleInternational journal of molecular sciences2025

A Dual-Template Molecularly Imprinted Polymer to Inhibit Quorum Sensing Molecules: Theoretical Design, Optimized Synthesis, Physicochemical Characterization and Preliminary Microbiological Analysis.

Khonzisizwe Somandi, Tama S Mwale, Monika Sobiech, Dorota Klejn, Gillian D Mahumane, Joanna Giebułtowicz, Sandy van Vuuren, Yahya E Choonara, Piotr Luliński

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khonzisizwe SomandiWits Advanced Drug Delivery Platform Research Unit, 7 York Road, Parktown, Johannesburg 2193, South Africa.
Tama S MwaleWits Advanced Drug Delivery Platform Research Unit, 7 York Road, Parktown, Johannesburg 2193, South Africa.
Monika SobiechDepartment of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0002-5687-2874
Dorota KlejnDepartment of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Gillian D MahumaneWits Advanced Drug Delivery Platform Research Unit, 7 York Road, Parktown, Johannesburg 2193, South Africa.ORCID 0000-0002-1734-3689
Joanna GiebułtowiczDepartment of Drug Chemistry, Pharmaceutical and Biomedical Analysis Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0002-2567-4453
Sandy van VuurenDepartment of Pharmacy and Pharmacology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg 2193, South Africa.ORCID 0000-0002-4859-1845
Yahya E ChoonaraWits Advanced Drug Delivery Platform Research Unit, 7 York Road, Parktown, Johannesburg 2193, South Africa.ORCID 0000-0002-3889-1529
Piotr LulińskiDepartment of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0001-8421-5225

Funding

Interdisciplinary Centre for Mathematical and Computational Modelling (ICM) at the University of Warsaw G68-2Medical University of Warsaw WF7/1/F/GW/N/24Medical University of Warsaw WF7/1/F/GW/N/25National Research Foundation (NRF) South Africa PPNT230823145247
6 · The paper itself

Abstract

Molecularly imprinted polymers (MIPs) have emerged as promising materials for selectively targeting biomolecules, including quorum sensing autoinducers that regulate bacterial communication and biofilm formation. In this study, both single-template and dual-template strategies were employed to design and synthesize MIPs capable of capturing autoinducer-2 analogs using (3R,4S)-tetrahydro-3,4-furandiol (

Indexed as

Molecularly Imprinted PolymersQuorum SensingAdsorptionAnti-Bacterial AgentsBiofilmsChromobacteriumHomoserineLactonesAnti-Bacterial AgentsHomoserineLactonesMolecularly Imprinted PolymersN-octanoylhomoserine lactoneanti-quorum sensingautoinducerautoinducer-2 analogdual template strategymolecular dockingmolecularly imprinted polymertheoretical designviolacein suppression

Identifiers

PMID40869335
PMCPMC12386585

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.