Evidence map›Paper›PMID 40869319›Full record

ReviewInternational journal of molecular sciences2025

Galectin-9-An Emerging Glyco-Immune Checkpoint Target for Cancer Therapy.

Anastasia Iris Karkempetzaki, Tobias Schatton, Steven R Barthel

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. LGALS9 Is Beneficial to the Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation on Ischemic Stroke.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
    Article
  3. Decoding Galectin-Glycan Recognition withJournal of the American Chemical Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. TIM-3 in AML: pathogenic roles and therapeutic targetability.Clinical and experimental medicine · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anastasia Iris KarkempetzakiDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Tobias SchattonDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Steven R BarthelDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Funding

Cell type-directed Tim-3 targeting in melanomaR01CA258637 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Steven Russell Barthel, Tobias Schatton · 2022 to 2026
$2.9M
Functional analysis of a novelintegrin-dependent metastasis pathway in melanomaR01CA247957 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BARTHEL, STEVEN RUSSELL, SCHATTON, TOBIAS · 2021 to 2025
$2.5M
NCI NIH HHS R01 CA247957NCI NIH HHS R01 CA258637NIH HHS 1R01CA247957-25NIH HHS 1R01CA258637-25
6 · The paper itself

Abstract

Galectin-9 (Gal-9,

Indexed as

GalectinsImmune Checkpoint InhibitorsNeoplasmsAnimalsHumansImmunotherapyTumor MicroenvironmentGalectinsImmune Checkpoint InhibitorsLGALS9 protein, humancancerGalectin-9galectinsglycobiologyimmune checkpointimmunotherapyPD-1TIM-3

Identifiers

PMID40869319
PMCPMC12386273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.