In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Olga V VolodinaLaboratory of Genome Editing, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0001-7086-2288 Anna G DemchenkoLaboratory of Genome Editing, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0002-4460-7627 Arina A AnuchinaLaboratory of Genome Editing, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0003-1820-5461 Oxana P RyzhkovaThe Shared Resource Centre "Genome", Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0003-1285-9093 Valeriia A KovalskayaThe Shared Resource Centre "Genome", Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0002-8728-8574 Ekaterina V KondratevaLaboratory of Genome Editing, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0003-0770-2569 Ekaterina V ArtemovaLaboratory of Genome Editing, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0009-0001-0997-9257 Vyacheslav Y TabakovThe Shared Resource Centre "Biobank", Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0003-0291-153X Maxim A IgnatovLaboratory of Radiation Biophysics, Department of Experimental Radiobiology and Radiation Medicine, State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC-FMBC), 123098 Moscow, Russia.ORCID 0000-0003-0381-5267 Natalia Y VorobyevaLaboratory of Radiation Biophysics, Department of Experimental Radiobiology and Radiation Medicine, State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC-FMBC), 123098 Moscow, Russia.ORCID 0000-0001-9008-4401 Andreyan N OsipovLaboratory of Radiation Biophysics, Department of Experimental Radiobiology and Radiation Medicine, State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC-FMBC), 123098 Moscow, Russia.ORCID 0000-0001-5921-9056 Alexander V LavrovLaboratory of Genome Editing, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0003-4962-6947 Svetlana A SmirnikhinaLaboratory of Genome Editing, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0002-1558-3048 Funding
The Ministry of Science and Higher Education of the Russian Federation for RCMG N/A
6 · The paper itselfAbstract
Prime editing is a promising approach for correcting pathogenic variants, but its efficiency remains variable across genomic contexts. Here, we systematically evaluated 12 modifications of the PEmax system for correcting the
Indexed as
Cystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorFlap EndonucleasesGene EditingCRISPR-Cas SystemsExodeoxyribonucleasesHumansCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorExodeoxyribonucleasesFlap Endonucleasescystic fibrosisEXO1FEN1gene editinggene therapyprime editing
Identifiers
PMID40869263
PMCPMC12386499
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