Evidence map›Paper›PMID 40869211›Full record

ArticleInternational journal of molecular sciences2025

Investigation of Pharmacological Mechanisms and Active Ingredients of

Xiaoye An, Yi Xu, Qiuyue Mao, Chengjin Lu, Xiaoyang Yin, Siying Chen, Bing Zhang, Zhijian Lin, Yu Wang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoye AnSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Yi XuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Qiuyue MaoSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Chengjin LuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Xiaoyang YinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Siying ChenSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.ORCID 0009-0009-9311-5184
Bing ZhangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Zhijian LinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.ORCID 0000-0001-5092-068X
Yu WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.ORCID 0000-0003-2265-3742

Funding

Beijing University of Chinese Medicine 2023 Qihuang Talent Plan Project K2023C03National Natural Science Foundation of China 82104475National Natural Science Foundation of China U20A20406
6 · The paper itself

Abstract

Renal urate deposition is a pathological inflammatory condition characterized by the accumulation of urate crystals in the kidneys, resulting from uric acid supersaturation.

Indexed as

ATP Binding Cassette Transporter, Subfamily G, Member 2Cichorium intybusHyperuricemiaKidneyLactonesMicroRNAsPlant ExtractsRNA, Long NoncodingSesquiterpenesUric AcidAnimalsDisease Models, AnimalGenes, ReporterLuciferasesMaleMolecular Docking SimulationAbcg2 protein, ratATP Binding Cassette Transporter, Subfamily G, Member 2H19 long non-coding RNALactonesLuciferasesMicroRNAsmirn21 microRNA, ratOxonic AcidPlant Extractspotassium oxonateRNA, Long NoncodingSesquiterpenesUric AcidABCG2active ingredientsCichorium intybus L.lncRNA H19/miR-21-3ppharmacological mechanismsrenal urate deposition

Identifiers

PMID40869211
PMCPMC12386761

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.