Evidence map›Paper›PMID 40869194›Full record

ArticleInternational journal of molecular sciences2025

A Single DNA Binding Site of DprA Dimer Is Required to Facilitate RecA Filament Nucleation.

Irina Bakhlanova, Begoña Carrasco, Aleksandr Alekseev, Maria Yakunina, Natalia Morozova, Mikhail Khodorkovskii, Michael Petukhov, Dmitry Baitin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irina BakhlanovaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Orlova Roscha 1, 188300 Gatchina, Russia.
Begoña CarrascoDepartment of Microbial Biotechnology, Centro Nacional de Biotecnología, CNB-CSIC, 3 Darwin Str., 28049 Madrid, Spain.ORCID 0000-0002-5671-1296
Aleksandr AlekseevResearch Center of Nanobiotechnologies, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russia.ORCID 0000-0003-4371-265X
Maria YakuninaResearch Center of Nanobiotechnologies, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russia.ORCID 0000-0003-2083-3643
Natalia MorozovaResearch Center of Nanobiotechnologies, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russia.ORCID 0000-0002-3001-2593
Mikhail KhodorkovskiiResearch Center of Nanobiotechnologies, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russia.ORCID 0000-0003-0562-0156
Michael PetukhovPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Orlova Roscha 1, 188300 Gatchina, Russia.ORCID 0000-0003-3771-1343
Dmitry BaitinResearch Center of Nanobiotechnologies, Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russia.ORCID 0000-0003-0022-1084

Funding

Consejo Superior de Investigaciones Científicas 202520E100
6 · The paper itself

Abstract

DprA (also known as Smf) is a conserved RecA mediator originally characterized by its role in natural chromosomal transformation, yet its widespread presence across bacteria hints at broader DNA metabolic functions. Here, we demonstrate that

Indexed as

Bacillus subtilisBacterial ProteinsDNA-Binding ProteinsDNA, Single-StrandedEscherichia coli ProteinsRec A RecombinasesAdenosine TriphosphateBinding SitesDNA, BacterialEscherichia coliMembrane ProteinsProtein BindingProtein MultimerizationAdenosine TriphosphateBacterial ProteinsDNA, BacterialDNA-Binding ProteinsDNA, Single-StrandedDprA protein, bacteriaEscherichia coli ProteinsMembrane ProteinsrecA protein, E coliRec A RecombinasesATP/dATP hydrolysisDpranucleoproteinsprotein–protein interactionsRecA

Identifiers

PMID40869194
PMCPMC12386762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.