Evidence map›Paper›PMID 40869043›Full record

ArticleInternational journal of molecular sciences2025

Not-So-Rare Defects of RBC Lipidic Composition: Four New Cases of Flippase Deficiency Due to

Elisa Fermo, Elena Trombetta, Anna Paola Marcello, Cristina Vercellati, Giulia Maria Ferrari, Anna Zaninoni, Valentina Brancaleoni, Elena Di Pierro, Sara Beneventi, Marta Tornese and 4 more

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. HypomorphicHemaSphere · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elisa FermoHematology, Physiopathology of Anemia Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Elena TrombettaFlow Cytometry Service, Clinical Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0002-1933-6415
Anna Paola MarcelloHematology, Physiopathology of Anemia Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Cristina VercellatiHematology, Physiopathology of Anemia Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0001-7742-1979
Giulia Maria FerrariPediatrics, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Anna ZaninoniHematology, Physiopathology of Anemia Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0002-8614-3904
Valentina BrancaleoniSC Medicina ad Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0003-1521-3319
Elena Di PierroSC Medicina ad Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0002-1413-1349
Sara BeneventiHematology, Physiopathology of Anemia Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Marta TorneseFlow Cytometry Service, Clinical Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0009-0004-0579-0934
Bruno FattizzoHematology, Physiopathology of Anemia Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Tommaso CasiniDepartment of Haematology-Oncology, Meyer University Children's Hospital, 50139 Firenze, Italy.ORCID 0000-0002-0087-5355
Paola CortiPediatrics, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Paola BianchiHematology, Physiopathology of Anemia Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0001-5976-5233

Funding

European Union's -MASCA Horizon 2020 - Acronym Innovation 101120168Italian Ministry of Health RC175/01
6 · The paper itself

Abstract

Adenosine Triphosphatase (ATPase) Phospholipid Transporting 11C gene (

Indexed as

Adenosine TriphosphatasesAnemia, HemolyticErythrocytesMutationAdultFemaleHumansMaleMembrane Transport ProteinsPedigreePhosphatidylserinesAdenosine TriphosphatasesATP11C protein, humanMembrane Transport ProteinsPhosphatidylserinesATP11Cflippasehemolysisphosphatidylserine exposure

Identifiers

PMID40869043
PMCPMC12387066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.