Evidence map›Paper›PMID 40869041›Full record

ArticleInternational journal of molecular sciences2025

HAT-PCR Enables Sensitive Quantification of Minimal Residual Disease in Chronic Lymphocytic Leukemia and Myeloma.

Elizabeth Hughes, Sue Latham, Bryone Kuss, Scott Grist, Rachel Hall, Tiffany Khong, Malgorzata Gorniak, Andrew Spencer, Constantine Tam, Stephen Mulligan and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Elizabeth HughesSchool of Medicine, Flinders University, Adelaide 5042, Australia.ORCID 0009-0007-3767-2758
Sue LathamSchool of Medicine, Flinders University, Adelaide 5042, Australia.
Bryone KussSchool of Medicine, Flinders University, Adelaide 5042, Australia.ORCID 0000-0002-5811-1331
Scott GristGenomix, Adelaide 5042, Australia.
Rachel HallGenomix, Adelaide 5042, Australia.
Tiffany KhongAlfred Hospital, Melbourne 3181, Australia.ORCID 0000-0002-9376-4223
Malgorzata GorniakAlfred Hospital, Melbourne 3181, Australia.
Andrew SpencerAlfred Hospital, Melbourne 3181, Australia.
Constantine TamAlfred Hospital, Melbourne 3181, Australia.
Stephen MulliganSchool of Medicine, University of Sydney, Sydney 2006, Australia.
Sheree BaileySchool of Medicine, Flinders University, Adelaide 5042, Australia.ORCID 0000-0001-6690-5476
Mary SartorSchool of Medicine, University of Sydney, Sydney 2006, Australia.
Dennis CarneyPeter MacCallum Clinic, Melbourne 3000, Australia.
Gavin CullSir Charles Gairdner Hospital, Perth 6009, Australia.
David GottliebSchool of Medicine, University of Sydney, Sydney 2006, Australia.
Alexander MorleySchool of Medicine, Flinders University, Adelaide 5042, Australia.ORCID 0000-0002-6122-5508

Funding

Monoquant 567.30485
6 · The paper itself

Abstract

The role of HAT-PCR (

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellMultiple MyelomaNeoplasm, ResidualPolymerase Chain ReactionAgedFemaleHigh-Throughput Nucleotide SequencingHumansImmunoglobulin Heavy ChainsMaleMiddle AgedImmunoglobulin Heavy Chainsacute lymphoblastic leukemiachronic lymphocytic leukemiadigital PCRflow cytometrymeasurable residual diseaseminimal residual diseasemyelomanext generation sequencingPCR

Identifiers

PMID40869041
PMCPMC12386463

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.