Evidence map›Paper›PMID 40868996›Full record

ArticleInternational journal of molecular sciences2025

Mouse Model of STAT3 Mutation Resulting in Job's Syndrome Diverges from Human Pathology.

Jakub Jankowski, Jichun Chen, Gyuhyeok Cho, Sung-Gwon Lee, Chengyu Liu, Neal Young, Jungwook Kim, Lothar Hennighausen

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jakub JankowskiSection of Genetics and Physiology, Laboratory of Cellular and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-1661-079X
Jichun ChenHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-1038-471X
Gyuhyeok ChoDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.ORCID 0000-0001-6785-616X
Sung-Gwon LeeSection of Genetics and Physiology, Laboratory of Cellular and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA.
Chengyu LiuTransgenic Core, National Heart, Lung, and Blood Institute, US National Institutes of Health, Bethesda, MD 20892, USA.
Neal YoungHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Jungwook KimDepartment of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.ORCID 0000-0001-5213-9299
Lothar HennighausenSection of Genetics and Physiology, Laboratory of Cellular and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0001-8319-9841

Funding

Intramural Research Programs, The National Heart, Lung, and Blood Institute (NHLBI) NAIntramural Research Programs, The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NANational Research Foundation of Korea (NRF) RS-2024-00411137, and RS-2024-00440614)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Job SyndromeMutationSTAT3 Transcription FactorAnimalsDisease Models, AnimalFemaleHumansMaleMicePhenotypesrc Homology DomainsStat3 protein, mouseSTAT3 Transcription Factorhyper-IgE syndromein-frame deletionSTAT3

Identifiers

PMID40868996
PMCPMC12387100

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.