Evidence map›Paper›PMID 40868776›Full record

ArticleGels (Basel, Switzerland)2025

Sodium Alginate/Carboxymethyl Chitosan Hydrogel Microbeads for Antibiotic Adsorption in Single and Binary Systems.

Zhisong Qian, Xinpeng Li, Gege Yan, Xiaoyong Chen, Mohd Shaiful Sajab, Gongtao Ding, Wan Nazihah Liyana Wan Jusoh

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhisong QianKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou 730030, China.
Xinpeng LiKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou 730030, China.
Gege YanKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou 730030, China.
Xiaoyong ChenKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou 730030, China.
Mohd Shaiful SajabDepartment of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia.ORCID 0000-0001-8400-8090
Gongtao DingKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou 730030, China.
Wan Nazihah Liyana Wan JusohDepartment of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia.ORCID 0009-0009-7672-7373

Funding

Fundamental Research Funds for the Central Universities, Northwest Minzu University 31920240064
6 · The paper itself

Abstract

The use of pharmaceuticals to treat human and animal diseases has resulted in the increase of antibiotic traces in the water system and soil, thus raising concerns about the environmental aspect. In this study, sodium alginate (SA) and carboxymethyl chitosan (CMCS) hydrogel microbeads were developed to enhance the adsorption of antibiotics by applying electrostatic spray in the fabrication of microbeads. Two hydrogel microbead sizes, SC-400 (~400 µm) and SC-2000 (~2000 µm), were used for the adsorption of tetracycline (TC) and ciprofloxacin (CIP) antibiotics in single and binary systems. The microbeads exhibited a good adsorption capacity and were able to achieve a maximum adsorption at pH 7 and 25 °C. Adsorption kinetics expressed suitability in the pseudo-second-order kinetic model for TC and CIP antibiotics. These results demonstrate that both single and binary systems align well with the Freundlich and Temkin isotherm models, indicating their suitability in explaining the adsorption mechanisms. These mechanisms predominantly involve electrostatic interactions between the SA/CMCS hydrogel microbeads and the antibiotics TC and CIP. This study highlights the capability of using SA/CMCS hydrogel microbeads for antibiotic removal and other environmental applications.

Indexed as

adsorptionantibioticsbiomaterialelectrostatic sprayinghydrogel microbeads

Identifiers

PMID40868776
PMCPMC12385651

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.