ArticleGels (Basel, Switzerland)2025
Quantum-Dot-Based Molecularly Imprinted Hydrogel for Rapid Detection of Homocysteine.
Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Elevated levels of homocysteine (Hcy) are associated with various pathological conditions including atherosclerosis, hypertension, and cardiovascular diseases. In this work, quantum-dot-based molecularly imprinted hydrogels (QD@MIHs) were developed by integrating L-cysteine-modified ZnS quantum dots (QDs)with highly selective molecular imprinting technology for rapid homocysteine detection. The QD@MIPHs were fabricated using a dual-functional monomer system (acrylamide and methacrylic acid) through surface coating of the Hcy molecularly imprinted polymer gel onto the QDs. Under optimal conditions, the response time of the QD@MIPHs for Hcy detection was 5 min. When the Hcy concentration ranged from 0.1 to 10.0 μM, the fluorescence quenching of the QD@MIHs showed a good linear relationship with Hcy concentration (
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