ArticleHealthcare (Basel, Switzerland)2025
Global, Regional, and National Burden of Burn Injury by Total Body Surface Area (TBSA) Involvement from 1990 to 2021, with Projections of Prevalence to 2050.
Article in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Artificial Intelligence in Burn and Wound Care: Image Analysis, Prediction, and Clinical Integration.Journal of burn care & research : official publication of the American Burn Association · 2026Review
- The Hidden Psychological Burden of Burn Injury: Clinical Characteristics Correlation of Psychiatric Disorders in Hospitalized Burn Patients at the Burn Unit of Dr. Cipto Mangunkusumo National General Hospital.European burn journal · 2026Article
- Infections in Burn Patients: Pathophysiology, Prevention, and Contemporary Therapeutic Strategies in the Era of Antimicrobial Resistance.Infectious diseases and therapy · 2026Review
- Sex differences in disease burden in China from 1990 to 2023 triangulating GBD and CHARLS.iScience · 2026Article
- Global inequalities in tracheal, bronchus, and lung cancer care quality from 1990 to 2021.iScience · 2026Article
- Clinical outcomes of pediatric burn injuries: A Single Center Study.Pakistan journal of medical sciences · 2026Article
- Functional Recovery and Emotional Burden After Burn Injury: A Quality of Life Assessment in Romanian Burn Survivors.Diseases (Basel, Switzerland) · 2026Article
- Therapeutic implications of epigenetic alterations in burns: a new frontier in burn medicine.Clinical science (London, England : 1979) · 2026Review
- Electrospun PLGA-Propolis Scaffolds Regulate Collagen Architecture in Burn Wounds.International journal of molecular sciences · 2026Article
- Neuromodulation strategies in postburn care for pain rehabilitation and scar remodelling.Communications medicine · 2026Review
- Optical, Tomographic, and Mass Spectrometry Imaging Methods for Burn Wounds: Capabilities, Limitations, and Clinical Potential.Biomedicines · 2026Review
- The role of microbial biosurfactants in enhancing wound repair: a comprehensive review.Folia microbiologica · 2026Review
- Clinical and epidemiological profiles of burns from a regional burn center in Egypt.Scientific reports · 2026Article
- Psycho-Socio-Cultural Determinants of Delayed Presentation for Specialized Burn Care and Their Clinical Consequences: A Mixed Observational Study.Journal of clinical medicine · 2026Article
- Lipid Nanoparticles Enable Efficient EGF mRNA Delivery for Wound Healing.Pharmaceutics · 2026Article
- Article
- Therapeutic Potential of Modulating Gene-MicroRNA Crosstalk in Burn Injury.International journal of molecular sciences · 2025Review
- Latent profiles of digital health literacy and perceived stigma in burn patients: a cross-sectional study.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesBurn injuries are a major public health concern. This study estimated global, regional, and national burn burdens by total body surface area from 1990 to 2021 and projected trends to 2050.
methodsUtilizing data from the Global Burden of Disease Study 2021, we examined the prevalence, mortality, and years lived with disability (YLDs) according to age, sex, and region. Future trends were predicted using Bayesian meta-regression models and Das Gupta decomposition analysis.
resultsIn 2021, global prevalence was 12.99 million for severe burns and 235.34 million for mild burns, with age-standardized rates of 158.75 and 2815.26 per 100,000. Severe burns were highest in Southern Latin America (7836.51 per 100,000) and mild burns in the Caribbean (626.94 per 100,000). The largest declines from 1990 to 2021 were in high-income North America for severe burns (-38.22%) and East Asia for mild burns (-73.03%). Females had higher severe burn prevalence at younger and older ages, while males had higher mild burn prevalence from early adulthood. Leading risk factors were fire, heat, and hot substances (38.22% of severe burn YLDs; 53.87% for mild burns). By 2050, severe burns are projected to rise by 233.4% and mild burns by 142.5%, with Eastern Europe showing the largest growth.
conclusionsAlthough age-standardized burn rates are declining, absolute cases are projected to rise due to population growth and aging, particularly in low- and middle-income countries, underscoring the need for stronger prevention and improved burn care infrastructure.
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