Evidence map›Paper›PMID 40868447›Full record

ArticleChildren (Basel, Switzerland)2025

Silent Struggles: Uncovering Mental Health Burdens in Adolescents with Inflammatory Bowel Disease and Juvenile Idiopathic Arthritis-A Retrospective Chart Review.

Kayla Beaudoin, Jaden Lo, Ethan Mewhinney, Kristen Bortolin, Tania Cellucci, Jenna Dowhaniuk, Liane Heale, Robert Issenman, Nikhil Pai, Mary Sherlock and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kayla BeaudoinFaculty of Health Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
Jaden LoFaculty of Health Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
Ethan MewhinneyFaculty of Health Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
Kristen BortolinDivision of Gastroenterology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Tania CellucciDivision of Rheumatology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0002-6022-495X
Jenna DowhaniukDivision of Gastroenterology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Liane HealeDivision of Rheumatology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Robert IssenmanDivision of Gastroenterology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Nikhil PaiDivision of Gastroenterology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0002-7537-6059
Mary SherlockDivision of Gastroenterology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Mary ZachosDivision of Gastroenterology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Christina GrantDivision of Adolescent Medicine, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Karen BeattieDivision of Rheumatology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Katherine ProwseDivision of Gastroenterology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.
Michelle BatthishDivision of Rheumatology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0001-6412-1029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesJuvenile idiopathic arthritis (JIA) and inflammatory bowel disease (IBD) are chronic autoimmune conditions that impact the physical and psychological well-being of pediatric patients. While previous studies have shown a high prevalence of mental health challenges among youth with chronic conditions, the prevalence of mental health issues in Canadian pediatric patients with JIA and IBD remains unclear. We aimed to estimate the prevalence of documented mental health disorders and related medication use of youth with JIA or IBD at a tertiary care centre.

methodsWe conducted a retrospective chart review of youths aged 12-17 diagnosed with JIA or IBD at McMaster Children's Hospital (MCH) to understand the prevalence of generalized anxiety disorder (GAD), separation anxiety disorder, social anxiety disorder (SAD), obsessive-compulsive disorders (OCD), eating disorders, major depressive disorder (MDD), adolescent adjustment disorder, suicide attempt/suicide ideation, self-harm behaviour, substance use disorder, and attention deficit disorders (ADD).

resultsWe reviewed 429 patient charts, including 303 patients with IBD and 126 with JIA. Our findings identified 90 IBD patients and 20 JIA patients who had one or more documented mental health conditions. Proportionately, there was a higher prevalence of mental health conditions among IBD patients (30%) compared to JIA patients (16%). The most frequently observed conditions in both IBD and JIA patients were GAD (63%, 50%), ADD (33%, 35%), and MDD (29%, 15%).

conclusionsThese findings highlight the critical need for early mental health screening and integrated care approaches that address both medical and psychosocial needs in adolescents with chronic illnesses. Future research should incorporate prospective study designs, include diverse geographic and demographic populations, and explore targeted interventions to improve mental and physical health outcomes in this vulnerable group.

Indexed as

inflammatory bowel diseasejuvenile idiopathic arthritismental healthyouth

Identifiers

PMID40868447
PMCPMC12384092

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.