ReviewBioengineering (Basel, Switzerland)2025
Evaluation of Surgical Protocols for Speech Improvement in Children with Cleft Palate: A Systematic Review and Case Series.
Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Meta-analysis of the skin redraping method and the Z-plasty method in the correction of epicanthus.Medicine · 2026Pooled it
- Solitary fibrous tumor of the oral cavity: a systematic review of the literature and a new clinicopathologic case report.Frontiers in oral health · 2026Pooled it
- The tooth transformer® revolution: autologous dentin biomaterials and platelet concentrates in oral regeneration. A parallel narrative systematic review.Frontiers in dental medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis systematic review investigates how different surgical techniques influence speech outcomes in children with cleft palate, focusing on the effectiveness of key palatoplasty methods and the timing of surgery on vocal function.
methodsA thorough search of the PubMed, Scopus, and Web of Science databases was conducted for studies published between 2014 and 2024, including clinical research reporting speech results after palatal repair, with bias assessed using the ROBINS tool. Additionally, two clinical cases are presented to demonstrate the practical application of the surgical approaches.
resultsAnalysis of fourteen studies revealed that modified Z-plasty and V-Y procedures enhance soft palate mobility and reduce hypernasality, although they require advanced surgical skills. Early closure of the hard palate, performed within the first year of life, was linked to improved consonant articulation compared to later surgeries. No significant differences were found between single-stage and two-stage repairs, but surgeon experience emerged as a crucial factor influencing outcomes.
conclusionsOverall, both the surgical technique selected and the timing of intervention play important roles in optimizing speech development in children affected by cleft palate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.