Evidence map›Paper›PMID 40868372›Full record

ArticleBioengineering (Basel, Switzerland)2025

Mitomycin C in Ahmed Glaucoma Valve Implant Affects Surgical Outcomes.

Wei-Chun Lin, Sen Yang, Michelle R Hribar, Aiyin Chen

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wei-Chun LinCasey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Rd, Portland, OR 97239, USA.
Sen YangCasey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Rd, Portland, OR 97239, USA.ORCID 0000-0002-0091-7498
Michelle R HribarCasey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Rd, Portland, OR 97239, USA.
Aiyin ChenCasey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Rd, Portland, OR 97239, USA.ORCID 0000-0002-2125-948X

Funding

TRAINING PROGRAM IN HEALTH INFORMATICST15LM007088 · NLM · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAM R HERSH, Vishnu Mohan · 1992 to 2026
$23.4M
Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
Operationalizing Machine Learning and Discrete Event Simulation Models to Improve Clinic EfficiencyR01LM013426 · NLM · OREGON HEALTH & SCIENCE UNIVERSITY · PI HRIBAR, MICHELLE · 2020 to 2023
$1.3M
Improving Quality of Electronic Health Record Ophthalmic Data for Big Data AnalyticsR21LM013937 · NLM · OREGON HEALTH & SCIENCE UNIVERSITY · PI WEISKOPF, NICOLE GRAY · 2021 to 2021
$187k
NEI NIH HHS P30 EY010572NIH HHS 1R21LM013937-24NLM NIH HHS R01 LM013426NLM NIH HHS R21 LM013937NLM NIH HHS T15 LM007088
6 · The paper itself

Abstract

Glaucoma is the leading cause of irreversible blindness worldwide, and the Ahmed Glaucoma Valve (AGV) implant is one of the most commonly performed surgeries to prevent glaucoma-related visual impairment. Mitomycin C is an anti-fibrotic agent that may prevent failure of AGV. This is a retrospective case-control study to evaluate surgical outcomes for patients undergoing AGV with adjunct mitomycin C (MMC) injections compared to those without MMC. Among the 142 eyes, 50 received adjunct MMC compared to 92 without MMC injections. IOPs at post-operative months 1, 3, and 6 were significantly lower in the MMC eyes (9.40, 12.01, 12.63 mmHg) compared to the No-MMC eyes (16.86, 15.87, 15.65 mmHg;

Indexed as

drug discoveryglaucomamitomycin Coutcome researchsurgerywound healing

Identifiers

PMID40868372
PMCPMC12383438

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.