Evidence map›Paper›PMID 40868363›Full record

ArticleBioengineering (Basel, Switzerland)2025

Extended Reality-Based Proof-of-Concept for Clinical Assessment Balance and Postural Disorders for Personalized Innovative Protocol.

Fabiano Bini, Michela Franzò, Alessia Finti, Francesca Tiberi, Veronica Maria Teresa Grillo, Edoardo Covelli, Maurizio Barbara, Franco Marinozzi

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In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabiano BiniDepartment of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.ORCID 0000-0002-5641-1189
Michela FranzòDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-6955-7534
Alessia FintiDepartment of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.ORCID 0009-0003-9658-7044
Francesca TiberiDepartment of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.
Veronica Maria Teresa GrilloDepartment of NESMOS, Otolaryngology Clinic, Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, Italy.
Edoardo CovelliDepartment of NESMOS, Otolaryngology Clinic, Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, Italy.
Maurizio BarbaraDepartment of NESMOS, Otolaryngology Clinic, Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0003-0740-0384
Franco MarinozziDepartment of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical assessment of balance and postural disorders is usually carried out through several common practices including tests such as the Subjective Visual Vertical (SVV) and Limit of Stability (LOS). Nowadays, several cutting-edge technologies have been proposed as supporting tools for stability evaluation. Extended Reality (XR) emerges as a powerful instrument. This proof-of-concept study aims to assess the feasibility and potential clinical utility of a novel MR-based framework integrating HoloLens 2, Wii Balance Board, and Azure Kinect for multimodal balance assessment. An innovative test is also introduced, the Innovative Dynamic Balance Assessment (IDBA), alongside an MR version of the SVV test and the evaluation of their performance in a cohort of healthy individuals.

resultsAll participants reported SVV deviations within the clinically accepted ±2° range. The IDBA results revealed consistent sway and angular profiles across participants, with statistically significant differences in posture control between opposing target directions. System outputs were consistent, with integrated parameters offering a comprehensive representation of postural strategies.

conclusionsThe MR-based framework successfully delivers integrated, multimodal measurements of postural control in healthy individuals. These findings support its potential use in future clinical applications for balance disorder assessment and personalized rehabilitation.

Indexed as

balance assessmentbalance disordersextended realityrehabilitationvestibular pathology

Identifiers

PMID40868363
PMCPMC12383928

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.