Evidence map›Paper›PMID 40868104›Full record

ArticleBiomedicines2025

Pleiotropic Effects of Oral Anticoagulant Therapy: Is There a Difference Between VKAs and DOACs?

Francesco Alfano, Anna Maria Gori, Martina Berteotti, Angela Rogolino, Francesca Cesari, Emilia Salvadori, Benedetta Formelli, Francesca Pescini, Carmen Barbato, Betti Giusti and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesco AlfanoDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.
Anna Maria GoriDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-6857-5861
Martina BerteottiDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-8281-4734
Angela RogolinoDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.
Francesca CesariDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.
Emilia SalvadoriDepartment of Biomedical and Clinical Sciences, University of Milan, 20157 Milan, Italy.ORCID 0000-0003-0404-0053
Benedetta FormelliNEUROFARBA Department, Neuroscience Section, University of Florence, 50134 Florence, Italy.
Francesca PesciniNEUROFARBA Department, Neuroscience Section, University of Florence, 50134 Florence, Italy.ORCID 0000-0003-4565-5601
Carmen BarbatoNEUROFARBA Department, Neuroscience Section, University of Florence, 50134 Florence, Italy.ORCID 0000-0003-4900-5008
Betti GiustiDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-8708-9444
Anna PoggesiNEUROFARBA Department, Neuroscience Section, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-8694-0129
Rossella MarcucciDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.

Funding

European Union Next Generation EU - NRRP M4C1, CUP: B83C22003920001European Union Next Generation EU - NRRP M6C2 - Investment 2.1 Enhancement and strengthening of biomed-ical research in the NHS, PNRR-MAD-2022-12376779, CUP C63C22001360006
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atrial fibrillationbiomarkersdirect oral anticoagulantsextracellular matrixhemostasishypofibrinolysisinflammationoral anticoagulant therapyvitamin K antagonist

Identifiers

PMID40868104
PMCPMC12383677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.