Evidence map›Paper›PMID 40867907›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Antioxidant Nanohybrid Materials Derived via Olive Leaf Extract Incorporation in Layered Double Hydroxide: Preparation, Characterization, and Evaluation for Applications.

Achilleas Kechagias, Areti A Leontiou, Alexios Vardakas, Panagiotis Stathopoulos, Maria Xenaki, Panagiota Stathopoulou, Charalampos Proestos, Emmanuel P Giannelis, Nikolaos Chalmpes, Constantinos E Salmas and 1 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Achilleas KechagiasDepartment of Food Science and Technology, University of Patras, 30100 Agrinio, Greece.
Areti A LeontiouDepartment of Food Science and Technology, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0003-0918-7759
Alexios VardakasDepartment of Food Science and Technology, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0003-0794-404X
Panagiotis StathopoulosDivision of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Maria XenakiPharmaGnose S.A., Papathanasiou 24, 34100 Chalkida, Greece.
Panagiota StathopoulouDepartment of Sustainable Agriculture, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0003-3941-0990
Charalampos ProestosLaboratory of Food Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771 Athens, Greece.ORCID 0000-0002-3450-5969
Emmanuel P GiannelisDepartment of Materials Science and Engineering, Cornell University, Ithaca, NY 14850, USA.
Nikolaos ChalmpesDepartment of Materials Science and Engineering, Cornell University, Ithaca, NY 14850, USA.ORCID 0000-0003-2744-5934
Constantinos E SalmasDepartment of Materials Science and Engineering, Cornell University, Ithaca, NY 14850, USA.ORCID 0000-0002-9475-9354
Aris E GiannakasDepartment of Food Science and Technology, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0003-3585-9045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, an innovative and sustainable strategy for the valorization of olive leaves, an underutilized agro-industrial byproduct, was developed through enzymatic-assisted aqueous extraction to produce a polyphenol-rich olive leaf extract (OLE). The extract contained notable concentrations of hydroxytyrosol (0.53 mg/L), luteolin-7-o-glucoside (0.70 mg/L), apigenin-4-o-glucoside (0.18 mg/L), and oleuropein (4.24 mg/L). For the first time, this OLE was successfully nanoencapsulated into layered double hydroxides (LDHs) synthesized at Zn

Indexed as

3 hydroxytyrosolantioxidant nanohybridsapigenin-4-o-glucosideenzymatic assisted extractionlayered double hydroxideluteolin-7-o-glucosideoleuropeinolive leaf extracttotal polyphenol content

Identifiers

PMID40867907
PMCPMC12382658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.