Evidence map›Paper›PMID 40867899›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Optimization of Conventional and Ultrasound-Assisted Extraction to Maximize Recovery of Total Phenolic Content and In Vitro Antioxidant Activity from

Zhanar Nabiyeva, Akerke Kulaipbekova, Serena Carpentieri, Yuliya Pronina, Abdyssemat Samadun, Elmira Assembayeva, Giovanna Ferrari

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Phytochemical Investigation ofAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Enhanced Recovery of Bioactive Compounds fromAntioxidants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhanar NabiyevaResearch Institute of Food Safety, Almaty Technological University, Almaty 050012, Kazakhstan.ORCID 0000-0001-7258-746X
Akerke KulaipbekovaDepartment of Food Technology, Almaty Technological University, Almaty 050012, Kazakhstan.ORCID 0000-0002-3878-8185
Serena CarpentieriDepartment of Industrial Engineering, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-0254-8307
Yuliya ProninaDepartment of Food Technology, Almaty Technological University, Almaty 050012, Kazakhstan.ORCID 0000-0003-0395-3379
Abdyssemat SamadunResearch Institute of Food Safety, Almaty Technological University, Almaty 050012, Kazakhstan.ORCID 0000-0002-5286-5175
Elmira AssembayevaDepartment of Food Technology, Almaty Technological University, Almaty 050012, Kazakhstan.
Giovanna FerrariDepartment of Industrial Engineering, University of Salerno, 84084 Fisciano, Italy.

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan AP23489874
6 · The paper itself

Abstract

background

methodsThe effects of temperature, extraction time, ethanol concentration, and solid-to-liquid ratio (or ultrasound power in the case of UAE) on total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (FRAP, DPPH, and ABTS assays) were systematically evaluated.

resultsThe UAE method yielded higher concentrations of TPC and TFC, with up to 16% improvement in TPC and reduced ethanol usage (40% (

conclusionsThese findings validate UAE as an innovative, eco-friendly method for extracting bioactive compounds from hawthorn leaves and highlight its potential for developing natural antioxidants for pharmaceutical and nutraceutical applications.

Indexed as

bioactive compoundsextractionhawthorn leavesHPLC-DADLC-Q/TOF-MSoptimizationultrasound

Identifiers

PMID40867899
PMCPMC12382680

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.