Evidence map›Paper›PMID 40867862›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Cardioprotective and Antihypertensive Effects of Topical Capsaicin in a Rat Model.

Juan Carlos Torres-Narváez, Vicente Castrejón-Téllez, María Sánchez-Aguilar, Agustina Cano-Martínez, Elizabeth Soria-Castro, Julieta Anabell Díaz-Juárez, Israel Pérez-Torres, Verónica Guarner-Lans, Elvira Varela-López, María de la Luz Ibarra-Lara and 4 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Juan Carlos Torres-NarváezDepartamento de Farmacología Dr. Rafael Méndez Martínez, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0002-3669-7482
Vicente Castrejón-TéllezDepartamento de Fisiología, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0002-8518-6961
María Sánchez-AguilarDepartamento de Farmacología Dr. Rafael Méndez Martínez, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0002-6697-0208
Agustina Cano-MartínezDepartamento de Fisiología, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Elizabeth Soria-CastroDepartamento de Biomedicina Cardiovascular, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Julieta Anabell Díaz-JuárezDepartamento de Farmacología Dr. Rafael Méndez Martínez, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Israel Pérez-TorresDepartamento de Biomedicina Cardiovascular, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0001-6510-2954
Verónica Guarner-LansDepartamento de Fisiología, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0002-2655-7590
Elvira Varela-LópezLaboratorio de Cardiología Translacional, Unidad de Investigación en Medicina Translacional UNAM/INCAR, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0001-5324-4664
María de la Luz Ibarra-LaraDepartamento de Farmacología Dr. Rafael Méndez Martínez, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0002-5106-5117
Gabriela Zarco-OlveraDepartamento de Farmacología Dr. Rafael Méndez Martínez, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Alvaro Vargas-GonzálezDepartamento de Fisiología, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0001-8189-2503
Pedro L Flores-ChávezDepartamento de Instrumentación Electromecánica, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Leonardo Del Valle-MondragónDepartamento de Farmacología Dr. Rafael Méndez Martínez, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.ORCID 0000-0002-2999-1050

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TRPV1 regulates neuronal and vascular function mediated by NO and CGRP. Systemic arterial hypertension (SAH) induces an imbalance in vascular mediators NO and CGRP by altering the transport of Ca

Indexed as

capsaicincell damageCGRPhypertensioninflammationTRPV1

Identifiers

PMID40867862
PMCPMC12383131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.