Evidence map›Paper›PMID 40867796›Full record

ArticleAntioxidants (Basel, Switzerland)2025

High-Fructose High-Fat Diet Renders the Retina More Susceptible to Blue Light Photodamage in Mice.

Meng-Wei Kao, Wan-Ju Yeh, Hsin-Yi Yang, Chi-Hao Wu

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng-Wei KaoGraduate Program of Nutrition Science, School of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan.
Wan-Ju YehGraduate Program of Nutrition Science, School of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan.ORCID 0000-0003-0723-3002
Hsin-Yi YangDepartment of Nutritional Science, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Chi-Hao WuGraduate Program of Nutrition Science, School of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan.ORCID 0000-0001-7243-3436

Funding

National Science and Technology Council of the Republic of China NSTC112-2320-B-003-001National Science and Technology Council of the Republic of China NSTC113-2320-B-003-002-MY3
6 · The paper itself

Abstract

Retinal degeneration is associated with dietary factors and environmental light exposure. This study investigated the effects of a high-fructose high-fat (HFHF) diet on susceptibility to blue light (BL)-induced retinal damage. Male ICR mice were randomized into three groups: control, BL alone, and BL plus HFHF diet (BL + HFHF). The BL + HFHF group consumed the HFHF diet for 40 weeks, followed by 8 weeks of low-intensity BL exposure (465 nm, 37.7 lux, 0.8 μW/cm

Indexed as

advanced glycation end productblue lighthigh-fructose high-fat dietoxidative stressphotochemical damageRAGEretina

Identifiers

PMID40867796
PMCPMC12382707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.