ArticleAnimals : an open access journal from MDPI2025
Differential Metabolomics and Cardiac Function in Trained vs. Untrained Yili Performance Horses.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- Exercise-specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring.Equine veterinary journal · 2026Article
- Mitochondrial Adaptations to Exercise Training in Equine Skeletal Muscle: A Narrative Review.Life (Basel, Switzerland) · 2026Review
- Article
- Cardiac-Metabolic Coupling Revealed by Lipid and Energy Metabolomics Determines 80 km Endurance Performance in Yili Horses.Biology · 2025Article
- Multi-Omics Deciphers Divergent Mechanisms in Differentially Cardiac-Remodeled Yili Horses Under Conditions of Equivalent Power Output.Animals : an open access journal from MDPI · 2025Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
This study aimed to investigate the effects of training on cardiac structure and function, as well as plasma metabolite profiles in horses, in order to uncover the molecular regulatory mechanisms and cardiac remodeling under long-term exercise. We hypothesize that long-term standardized training induces physiological cardiac remodeling and differential metabolomic changes in Yili horses, which correlate with improved athletic performance. The study focuses on physiological exercise-induced cardiac remodeling, characterized by increased left ventricular wall thickness and chamber size. A total of 18 Yili horses, a unique Chinese equine breed, were included in the study of equine exercise physiology. Twelve horses underwent six months of standardized training followed by three 1000 m performance tests. Based on final rankings, they were divided into an advanced group (AG, top six horses) and a habitual group (HG, bottom six horses). The remaining six untrained horses served as the untrained group (UG), with only free-range activity. Echocardiographic results revealed significant differences (
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Registered trials
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