Evidence map›Paper›PMID 40867681›Full record

ArticleAnimals : an open access journal from MDPI2025

Transcriptomics Analysis of the Adipogenic Differentiation Mechanism of Bovine Adipose-Derived Neural Crest Stem Cells.

Kai Zhang, Xiaopeng Tang, Rui Zhao, Yibo Yan, Xianyi Song

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kai ZhangCollege of Animal Science, Shanxi Agricultural University, Taiyuan 030032, China.ORCID 0000-0002-8784-493X
Xiaopeng TangState Engineering Technology Institute for Karst Desertfication Control, School of Karst Science, Guizhou Normal University, Guiyang 550025, China.ORCID 0000-0002-4789-5687
Rui ZhaoCollege of Animal Science, Shanxi Agricultural University, Taiyuan 030032, China.
Yibo YanCollege of Animal Science, Shanxi Agricultural University, Taiyuan 030032, China.
Xianyi SongCollege of Animal Science, Shanxi Agricultural University, Taiyuan 030032, China.

Funding

Fundamental Research Program of Shanxi Province 202303021221095Guizhou Provincial Science and Technology Foundation Qiankehe Jichu-ZK [2023] Yiban 267Shanxi Agricultural University's Research Initiation Program for Recruited Talents (2023BQ56Shanxi Agricultural University's Technology Innovation Advancement Project Program CXGC2023012
6 · The paper itself

Abstract

The aim of the present study was to investigate the expression of related genes during the differentiation process of baNCSCs into adipocytes using transcriptomics technique, thereby clarifying the potential mechanism underlying baNCSCs differentiation into adipocytes and providing insights into lipid metabolism and regulation of lipid deposition in ruminants. Transcriptomic analysis was conducted on the adipocytes of baNCSCs on days 0 (CON0), 3 (DIF3), and 9 (DIF9) of differentiation. The results showed that in the early stage of adipocyte differentiation of baNCSCs, differentially expressed genes (DEGs) are mainly involved in metabolic pathways such as chromosome modification, cell cycle progression, and regulation of stem cell pluripotency. In the middle and late stages of differentiation, DEGs are mainly involved in metabolic pathways such as changes in cell morphology and synthesis of fatty acids and triglycerides. Predicting the top 10 core hub genes (CHGs) in the protein-protein interaction (PPI) network that regulate various differentiation stages of adipocytes reveals that

Indexed as

adipogenic differentiationbovine adipose-derived neural crest stem cellsdifferentially expressed genestranscriptomics

Identifiers

PMID40867681
PMCPMC12383184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.