Histone H3 N-Terminal Tail Residues Important for Meiosis in

Amy Prichard, Marnie Johansson, David T Kirkpatrick, Duncan J Clarke

Abstract read

In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amy PrichardDepartment of Genetics, Cell Biology & Development, University of Minnesota, Minneapolis, MN 55455, USA.

Marnie JohanssonDepartment of Genetics, Cell Biology & Development, University of Minnesota, Minneapolis, MN 55455, USA.

David T KirkpatrickDepartment of Genetics, Cell Biology & Development, University of Minnesota, Minneapolis, MN 55455, USA.

Duncan J ClarkeDepartment of Genetics, Cell Biology & Development, University of Minnesota, Minneapolis, MN 55455, USA.

Funding

Control of Chromosome Segregation by DNA Topoisomerase IIR01GM130858 · NIGMS · UNIVERSITY OF MINNESOTA · PI DUNCAN J. CLARKE · 2019 to 2026

$2.2M

NIGMS NIH HHS R01 GM130858NIH HHS GM130858

6 · The paper itself

Abstract

Histone tail phosphorylation has diverse effects on a myriad of cellular processes, including cell division, and is highly conserved throughout eukaryotes. Histone H3 phosphorylation at threonine 3 (H3T3) during mitosis occurs at the inner centromeres and is required for proper biorientation of chromosomes on the mitotic spindle. While H3T3 is also phosphorylated during meiosis, a possible role for this modification has not been tested. Here, we asked if H3T3 phosphorylation is important for meiotic division by quantifying sporulation efficiency and spore viability in

Indexed as

HistonesMeiosisSaccharomyces cerevisiaeMutationPhosphorylationSaccharomyces cerevisiae ProteinsSpores, FungalThreonineHistonesSaccharomyces cerevisiae ProteinsThreonineH3T3histone H3histone modificationsmeiosisphosphorylationsporulation

Identifiers

PMID40867646

DOI10.3390/biom15081202

PMCPMC12384203

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.