Evidence map›Paper›PMID 40867617›Full record

ArticleBiomolecules2025

Hepatic Expression of ACBP Is a Prognostic Marker for Weight Loss After Bariatric Surgery.

Moritz Meyer, Paul Gruber, Christina Plattner, Barbara Enrich, Andreas Zollner, Almina Jukic, Maria Effenberger, Christoph Grander, Herbert Tilg, Felix Grabherr

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Moritz MeyerDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Paul GruberDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0009-0004-1678-5962
Christina PlattnerBiocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-3217-3278
Barbara EnrichDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Andreas ZollnerDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-6095-068X
Almina JukicDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Maria EffenbergerDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christoph GranderDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Herbert TilgDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-4235-2579
Felix GrabherrDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, and Metabolism, Medical University of Innsbruck, 6020 Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence and prevalence of obesity and related cardio-metabolic diseases are on the rise, posing a critical health care challenge to systems across the globe. Bariatric surgery is a therapeutic cornerstone for morbidly obese patients, besides novel medical treatments, partly by ameliorating metabolic inflammation, a hallmark of metabolic diseases. Acyl-CoA Binding Protein (ACBP), also known as diazepam-binding inhibitor (DBI), is a regulator of autophagy and metabolism, and has recently been shown to increase in individuals undergoing voluntary fasting and in patients with cancer cachexia-induced malnutrition. By analyzing a prospectively collected study with matched serum and liver samples from patients undergoing laparoscopic adjustable gastric banding at baseline and six months after surgery, we here demonstrate that ACBP serum levels significantly increase following bariatric surgery. Hepatic

Indexed as

Bariatric SurgeryDiazepam Binding InhibitorLiverObesity, MorbidWeight LossAdultBiomarkersFemaleHumansMaleMiddle AgedPrognosisBiomarkersDiazepam Binding InhibitorACBPbariatric surgeryDBIweight loss

Identifiers

PMID40867617
PMCPMC12384758

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.