Evidence map›Paper›PMID 40867569›Full record

ArticleBiomolecules2025

Promotion of Bone Defect Repair Using Decellularized Antler Cancellous Bone Loaded with Deer Osteoglycin.

Yusu Wang, Ying Zong, Weijia Chen, Naichao Diao, Quanmin Zhao, Boyin Jia, Miao Zhang, Jianming Li, Yan Zhao, Zhongmei He and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yusu WangCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.ORCID 0009-0005-5373-7561
Ying ZongCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0003-0730-0519
Weijia ChenCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Naichao DiaoCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Quanmin ZhaoCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Boyin JiaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Miao ZhangCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Jianming LiCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Yan ZhaoCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0003-0704-7410
Zhongmei HeCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Rui DuCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.

Funding

Jilin Provincial Department of science and technology 20220304001YY; 20220304002YY; 20240601086RC; RJTG202402; YDZJ202502CXJD077
6 · The paper itself

Abstract

The combination of scaffold materials and bioactive factors is a promising strategy for promoting bone defect repair in tissue engineering. Previous studies have shown that osteoglycin (OGN) is highly expressed in the bone repair process using deer antler as an animal model of bone defects. It suggests that OGN may be a key active component involved in the bone repair process. The aim of this study was to investigate whether deer OGN (dOGN) could effectively promote bone regeneration. We successfully expressed dOGN using the

Indexed as

AntlersBone RegenerationCancellous BoneAnimalsCell MovementCell ProliferationDeerOsteogenesisTissue EngineeringTissue Scaffoldsbioactive factorsbone defect repairdecellularized antler cancellous bonedeer osteoglycinenhanced bone healing

Identifiers

PMID40867569
PMCPMC12383809

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.