ArticleBiomolecules2025
Association of 17q12-q21 Asthma Risk Locus with Clinical Severity of Infant Respiratory Syncytial Virus Infection.
Kedir N Turi, Christopher McKennan, Christian Rosas-Salazar, Tebeb Gebretsedik, Dawn C Newcomb, Emma E Thompson, James Gern, James Chappell, Larry Anderson, Carole Ober and 1 more
Abstract read
In one paragraphArticle in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Kedir N TuriDepartment of Epidemiology and Biostatistics, Indiana University, 1025 E Seventh St., Bloomington, IN 47405, USA.ORCID 0000-0002-3853-9357 Christopher McKennanDepartment of Statistics, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Christian Rosas-SalazarDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Tebeb GebretsedikDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37203, USA.
Dawn C NewcombDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Emma E ThompsonDepartment of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
James GernDepartment of Pediatrics, University of Wisconsin, Madison, WI 53705, USA.
James ChappellDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Tina HartertDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0001-7470-1166 Funding
Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7MWisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8MViral and Host Determinants of Infant and Childhood Allergy and AsthmaU19AI095227 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Dawn C Newcomb · 2011 to 2026
$34.9MIdentification of Early Metabolomic and Immune Endotypes of Allergy and Asthma: An Integrated Multiomics ApproachK01HL149989 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TURI, KEDIR NESHA · 2020 to 2024
$810kNational Institute of Health K01HL149989NCATS NIH HHS UL1 TR002243NHLBI NIH HHS K01 HL149989NIAID NIH HHS U19 AI095227NIH HHS UH3 OD023282
6 · The paper itselfAbstract
This study examined whether SNPs at the 17q12-q21 locus that are associated with childhood asthma are also associated with severe respiratory syncytial virus (RSV) infection and viral load. We conducted a candidate SNP association study in the subset of RSV-infected infants who were parent-identified as White (
Indexed as
AsthmaChromosomes, Human, Pair 17Respiratory Syncytial Virus InfectionsFemaleGenetic Predisposition to DiseaseHumansInfantMalePolymorphism, Single NucleotideSeverity of Illness IndexViral Load17q12-q21-locusasthmainfantinfectionrespiratory syncytial virus (RSV)viral load
Identifiers
PMID40867500
PMCPMC12383441
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