Evidence map›Paper›PMID 40867297›Full record

ArticleCancers2025

Impact of Preoperative CT-Diagnosed Sarcopenic Obesity on Outcomes After Radical Cystectomy for Bladder Cancer.

Alberto Artiles Medina, Mariam Bajawi Carretero, Enrique López Pérez, Sara Garach Fernández, David López Curtis, Leyre Elías Pascual, José Daniel Subiela, Javier Soto Pérez-Olivares, Catalina Nieto Góngora, Fernando González Tello and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alberto Artiles MedinaUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.ORCID 0000-0003-0930-0344
Mariam Bajawi CarreteroDepartment of General Surgery, University Hospital of Guadalajara, 19002 Guadalajara, Spain.ORCID 0000-0003-4952-6233
Enrique López PérezUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.
Sara Garach FernándezUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.
David López CurtisUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.ORCID 0000-0002-5986-3690
Leyre Elías PascualBiomedical Engineering, Universidad Politécnica de Madrid (UPM), 28034 Madrid, Spain.
José Daniel SubielaUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.ORCID 0000-0003-4176-8174
Javier Soto Pérez-OlivaresEngineering & Innovation Unit, Radiology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain.ORCID 0000-0002-0858-1394
Catalina Nieto GóngoraEngineering & Innovation Unit, Radiology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain.
Fernando González TelloRadiology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain.
Irene de la Parra SánchezUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.ORCID 0000-0002-4064-9133
César Mínguez OjedaUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.ORCID 0000-0002-4188-3298
Victoria Gómez Dos SantosUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.ORCID 0000-0003-2968-148X
Francisco Javier Burgos RevillaUrology Department, Ramón y Cajal University Hospital, University of Alcalá, 28034 Madrid, Spain.ORCID 0000-0002-0758-5414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the impact of body composition parameters, including specifically sarcopenic obesity (SO), on postoperative and oncological outcomes in patients undergoing radical cystectomy (RC) for bladder cancer, thereby addressing a paucity of data in this setting.

methodsA retrospective observational study was conducted in patients who underwent RC. Preoperative CT scans were analyzed using semi-automatic segmentation software to assess body composition parameters, with measurements of adipose and muscle tissue obtained at the level of the L3 vertebra.

resultsA total of 249 patients were included, of whom 127 (52.5%) met the criteria for sarcopenia, 53 (21.3%) for obesity, and 14 (5.6%) for SO. Multivariate analysis identified previous abdominal surgery (OR 2.56, 95% CI 1.24-5.23,

conclusionsPreoperative CT-based assessment of body composition is a valuable tool in the surgical evaluation of patients undergoing RC. SO appears to be an independent predictor of short-term postoperative complications and should be considered when planning prehabilitation strategies.

Indexed as

bladder cancerbody compositioncystectomyobesitysarcopeniasarcopenic obesity

Identifiers

PMID40867297
PMCPMC12384084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.