Evidence map›Paper›PMID 40867246›Full record

ArticleCancers2025

Brightly Visualizing Pancreatic Cancer Margins in Orthotopic Mouse Models with an Anti-CA19-9 Antibody Conjugated to a Near-Infrared Fluorophore.

Kristin E Cox, Javier Bravo, Sunidhi Jaiswal, Siamak Amirfakhri, Thinzar M Lwin, Abhijit Aithal, Sumbal Talib, Lily J Jih, Aylin Din Parast Saleh, Keita Kobayashi and 6 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kristin E CoxDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.ORCID 0000-0001-8621-1869
Javier BravoDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.
Sunidhi JaiswalDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.
Siamak AmirfakhriDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.
Thinzar M LwinDepartment of Surgical Oncology, City of Hope National Medical Center, Duarte, CA 91010, USA.ORCID 0000-0003-1820-088X
Abhijit AithalDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0001-9035-7529
Sumbal TalibFred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0001-7141-740X
Lily J JihVA San Diego Healthcare System, La Jolla, CA 92161, USA.
Aylin Din Parast SalehDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.
Keita KobayashiDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.ORCID 0009-0004-9177-2352
Kavita MallyaDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Maneesh JainDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-2020-3687
Robert M HoffmanDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.
Aaron M MohsFred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-9353-5404
Surinder K BatraDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0001-9470-9317
Michael BouvetDepartment of Surgery, University of California San Diego, La Jolla, CA 92092, USA.

Funding

UCSD Cancer Center Training Program in Drug DevelopmentT32CA121938 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Michael Bouvet, Dwayne G. Stupack · 2006 to 2026
$10.3M
Molecular Imaging Probe(s) for Optical Surgical Navigation of Pancreatic CancerR01CA256973 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Surinder K. Batra, Michael Bouvet · 2022 to 2026
$2.2M
Preclinical development of a novel antibody conjugate for intraoperative detection of pancreatic cancerR01CA259080 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Aaron M. Mohs · 2022 to 2026
$1.8M
BLRD VA I01 BX003856M.B. and S.K.B. R01 CA256973, T32CA121938, R01 CA259080NCI NIH HHS R01 CA256973NCI NIH HHS R01 CA259080NCI NIH HHS T32 CA121938
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CA19-9fluorescence-guided surgeryfluorescent imagingorthotopic mouse modelpancreatic cancerSPYtumor marker

Identifiers

PMID40867246
PMCPMC12385055

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.