Evidence map›Paper›PMID 40867188›Full record

ReviewBrain sciences2025

Balancing Risk and Reward: Dopamine's Central Role in Economic Decision-Making.

Luca Aquili, Lee Wei Lim

Abstract readReview
In one paragraph

Review in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Luca AquiliSchool of Management, Ritsumeikan Asia Pacific University, Beppu 874-0011, Japan.ORCID 0000-0003-4930-1536
Lee Wei LimDrLim Neuromodulation Lab, Department of Biosciences and Bioinformatics, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.ORCID 0000-0001-6692-6285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine has been increasingly implicated in shaping economic and financial decision-making, yet much of the evidence remains fragmented across paradigms and mechanistic levels, and heavily based on preclinical or clinical populations. This review synthesises pharmacological, neuroimaging, and genetic findings from studies involving healthy human participants, highlighting dopamine's role in risk-taking, delay discounting, social fairness, reward sensitivity, and feedback learning. It distinguishes between transient state-related effects and stable trait-level influences, and clarifies how dopaminergic tone, receptor subtype activity-particularly D2-and corticostriatal circuitry modulate economic choices. In doing so, the review advances a mechanism-focused framework for understanding adaptive and biased decision strategies.

Indexed as

dopaminefinancial decision-makingreinforcement learningrewardrisk

Identifiers

PMID40867188
PMCPMC12384306

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.