Evidence map›Paper›PMID 40867135›Full record

ArticleBrain sciences2025

Considering Litter Effects in Preclinical Research: Evidence from E17.5 Acid-Sensing Ion Channel 2a Knockout Mice Exposed to Acute Seizures.

Junie P Warrington, Tyranny Pryor, Maria Jones-Muhammad, Qingmei Shao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junie P WarringtonDepartment of Neurology, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0001-5626-8872
Tyranny PryorDepartment of Neurology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Maria Jones-MuhammadProgram in Neuroscience, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0002-3078-2096
Qingmei ShaoDepartment of Neurology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

Funding

The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, JOHN E · 2013 to 2022
$23.4M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Center for Psychiatric NeuroscienceP30GM103328 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI STOCKMEIER, CRAIG ALLEN · 2013 to 2017
$5.5M
Cerebrovascular Abnormalities in PreeclampsiaR00HL129192 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI WARRINGTON, JUNIE PAULA · 2017 to 2019
$909k
American Physiological Society William Townsend Porter FellowshipNHLBI NIH HHS R00 HL129192NHLBI NIH HHS R00HL129192NHLBI NIH HHS R00HL129192-S1NHLBI NIH HHS T32 HL105324NHLBI NIH HHS T32HL105324NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20GM104357NIGMS NIH HHS P30 GM103328NIGMS NIH HHS P30GM103328
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ASIC2alitter effectseizuresex differencesuterine position

Identifiers

PMID40867135
PMCPMC12384535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.