Evidence map›Paper›PMID 40866907›Full record

ArticleBMC ophthalmology2025

Efficacy and safety of Nd: YAG laser vitreolysis in patients with physiological vitreous floaters.

Junjie Liu, Huilin Liu, Ying Zhang, Yichen Zheng, Jing Li, Chao Pan, Ke Jiang, Jianhong Cheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Junjie Liu *Wuhan Aier Hankou Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.328,Machang Street, Jianghan District, Wu Han, 320000, China.
Huilin Liu *Wuhan Aier Hankou Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.328,Machang Street, Jianghan District, Wu Han, 320000, China.
Ying ZhangWuhan Aier Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.481, Zhongshan Road, Wuchang District, WuHan, 320000, China.
Yichen ZhengWuhan Aier Hankou Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.328,Machang Street, Jianghan District, Wu Han, 320000, China.
Jing LiWuhan Aier Hankou Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.328,Machang Street, Jianghan District, Wu Han, 320000, China.
Chao PanWuhan Aier Hankou Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.328,Machang Street, Jianghan District, Wu Han, 320000, China.
Ke JiangWuhan Aier Hankou Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.328,Machang Street, Jianghan District, Wu Han, 320000, China.
Jianhong ChengWuhan Aier Hankou Eye Hospital, Aier Eye Hospital Affiliated to Wuhan University, No.328,Machang Street, Jianghan District, Wu Han, 320000, China. 29238368@qq.com.

Funding

Wuhan Municipal Health Commission WX20D39
6 · The paper itself

Abstract

purposeTo observe the clinical effects of Nd: YAG laser vitreolysis in patients with physiological vitreous floaters by A/B ultrasound and infrared fundus photography., and to evaluate the safety of the treatment by ffERG.

methodsThirty eyes diagnosed with physiological vitreous floaters were enrolled. Examination of BCVA, IOP, SLO, A/B ultrasound, infrared fundus photography and ffERG were performed. The vitreolysis was performed for all patients by the same skilled doctor using an ELLEX YAG laser vitreolysis machine. The IOP was measured half an hour after the operation. After treatment, the patients were followed up at 1 day, 1 week, and 1 month. At follow-up, the same thorough examination as before the operation was performed. ImageJ software was used to measure the size of the vitreous floaters in the infrared fundus photography pictures before and after treatment.

resultsThere was no significant difference in BCVA and IOP before and after treatment (p > 0.05). Infrared fundus photography showed that the vitreous floaters were obviously reduced or disappeared after treatment, and the difference was statistically significant (p < 0.01). The latent period and amplitude of the five response waves of ffERG at each timepoint were compared before and after treatment, and there was no significant difference (P > 0.05). Ultra-wide angle SLO showed no severe complications in the vitreous or retina after treatment.

conclusionsIn short-term observations, Nd: YAG laser vitreolysis is safe and effective for the treatment of vitreous floaters and can be promoted clinically.

Indexed as

Eye DiseasesLasers, Solid-StateLaser TherapyVitrectomyVitreous BodyAdultAgedElectroretinographyFemaleFollow-Up StudiesHumansIntraocular PressureMaleMiddle AgedTreatment OutcomeVision DisordersA/B ultrasoundFull-field electroretinogramInfrared fundus photographyNd: YAG laser vitreolysisPhysiological vitreous floaters

Identifiers

PMID40866907
PMCPMC12382255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.