Evidence map›Paper›PMID 40866748›Full record

ArticleJournal of general internal medicine2026

Measuring the Impact of a Multi-Site In-Hospital Intervention for Opioid Use Disorder Treatment Provision: A Survey of Hospital-Based Clinicians.

Susan L Calcaterra, Steven Lockhart, Crystal Natvig, Susan K Mikulich-Gilbertson

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06291090 (In Hospital Treatment of Opioid Use Disorder), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06291090 nacompletednot on this map

In Hospital Treatment of Opioid Use Disorder: Clinician Perspectives and Current Practices

TypeinterventionalSponsorUniversity of Colorado, DenverRan2023 to 2025Enrolled400ConditionsOpioid Use DisorderArmsOUD treatment intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susan L CalcaterraDepartment of Medicine, Division of Hospital Medicine, University of Colorado, Aurora, CO, USA. susan.calcaterra@cuanschutz.edu.ORCID 0000-0002-0584-7783
Steven LockhartDepartment of Medicine, Division of General Internal Medicine, Adult and Child Center for Health Outcomes Research and Delivery Service, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.
Crystal NatvigAdult and Child Center for Health Outcomes Research, Department of Psychiatry, University of Colorado, Aurora, CO, USA.
Susan K Mikulich-GilbertsonAdult and Child Center for Health Outcomes Research, Department of Psychiatry, University of Colorado, Aurora, CO, USA.

Funding

Understanding Factors that Limit Access to Opioid Use Disorder Treatment in the Hospital to Inform Innovative Approaches to Expand Hospital-Based TreatmentK08DA049905 · NIDA · UNIVERSITY OF COLORADO DENVER · PI CALCATERRA, SUSAN L · 2020 to 2024
$945k
NIDA NIH HHS K08 DA049905NIDA NIH HHS K08DA049905
6 · The paper itself

Abstract

backgroundOpioid-related hospitalizations are highly prevalent. Hospital-based clinicians are well positioned to initiate medications for opioid use disorder (MOUD) among hospitalized adults with OUD.

objectiveMeasure the perceived impact of a multi-site and multi-faceted OUD intervention to expand provision of hospital-based OUD treatment, including MOUD. DESIGN, PARTICIPANTS, AND

settingCompared pre- and post-OUD intervention survey results of hospital-based clinicians practicing across 12 hospitals following implementation of an OUD intervention. MEASURES: Survey questions were grouped into six domains: evidence to treat OUD; hospital processes to screen for unhealthy substance use and refer to post-discharge OUD treatment; MOUD initiation; readiness to initiate MOUD; current practices to initiate MOUD; and leadership prioritization of OUD treatment. We calculated mean summary scores across domains and measured changes across pre- and post-OUD intervention surveys. We analyzed open-ended survey questions using a team-based content analysis to identify and quantify key concepts. KEY

resultsOf the 213 post-OUD intervention survey respondents (61% response rate), 110 (52%) also completed the pre-survey. Compared to the pre-survey, in the post-survey, more respondents reported believing that the evidence to treat OUD was valid (p < 0.001), reported higher satisfaction with hospital processes to screen and refer to OUD treatment (p < 0.001), reported fewer concerns regarding MOUD initiation (buprenorphine: p < 0.001; methadone: p < 0.001), reported that leadership prioritized OUD treatment (p < 0.001), and reported higher readiness to initiate MOUD (buprenorphine: p < 0.001; methadone: p < 0.001). Fewer respondents reported barriers to initiate buprenorphine (p = 0.002) or methadone (p < 0.001) in the hospital. Emergent key concepts from open-ended questions included a need for ongoing education and training to treat OUD and a need for access to addiction specialists (n = 50%; n = 28% of write-in responses, respectively).

conclusionInterventions to facilitate in-hospital OUD treatment should address local barriers to providing this care, including ensuring access to addiction specialists and providing routine and accessible education to hospital-based clinicians.

Indexed as

Opiate Substitution TreatmentOpioid-Related DisordersAdultFemaleHospitalizationHumansMaleMethadoneMiddle AgedSurveys and QuestionnairesMethadoneHospital-based clinicianMedications for opioid use disorderOpioid use disorderSubstance use disorder

Identifiers

PMID40866748
PMCPMC12718543

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.