Evidence map›Paper›PMID 40866721›Full record

ArticleEJNMMI physics2025

Bridging physics and practice: evaluating sensitivity, septal penetration, and detector dead time in terbium-161 gamma-camera imaging.

Frida Westerbergh, Lisa McDougall, Philipp Ritt, Julia G Fricke, Nicholas P van der Meulen, Cristina Müller, Roger Schibli, Damian Wild, Peter Bernhardt

Abstract read
In one paragraph

Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. QuantitativeEJNMMI physics · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Frida WesterberghDepartment of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gula Stråket 2B, Gothenburg, 413 45, Sweden. frida.westerbergh@gu.se.ORCID http://orcid.org/0009-0006-3704-7357
Lisa McDougallDivision of Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
Philipp RittITM Oncologics GmbH, Lichtenbergstrasse 1, 85748, Garching, Munich, Germany.
Julia G FrickeDivision of Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
Nicholas P van der MeulenLaboratory of Radiochemistry, PSI Center for Nuclear Engineering and Sciences, Villigen-PSI, Villigen, Switzerland.
Cristina MüllerCenter for Radiopharmaceutical Sciences, PSI Center for Life Sciences, Villigen-PSI, Villigen, Switzerland.
Roger SchibliCenter for Radiopharmaceutical Sciences, PSI Center for Life Sciences, Villigen-PSI, Villigen, Switzerland.
Damian WildDivision of Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
Peter BernhardtDepartment of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gula Stråket 2B, Gothenburg, 413 45, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION/

aimTerbium-161 (

methodsMeasurements were conducted on a Siemens Symbia Intevo system using two collimators: low-energy high-resolution (LEHR) and medium-energy low-penetration (MELP). Two energy windows were evaluated: 75 keV ± 10% and 48 keV ± 20%. Planar sensitivity and penetration were assessed using a

resultsSensitivity was comparable for both collimators at 75 keV (LEHR: 15.7 cps/MBq, MELP: 18.5 cps/MBq) and increased at 48 keV (LEHR: 44.4 cps/MBq, MELP: 67.9 cps/MBq). Maximum penetration occurred at 75 keV with the LEHR collimator (7.5% at 10 cm). In acquired spectra, more than half of the detected counts (51.6%) appeared above the 75 keV window with LEHR, compared to only 12.2% with MELP. Dead-time analyses revealed non-linear detector responses at wide-spectrum count rates exceeding 93 kcps, corresponding to in-field activities of 1.4-2.0 GBq for LEHR and 1.7-2.2 GBq for MELP. The dead-time constant was determined to 0.42 µs for both detector heads, however, the maximum recorded count rate differed significantly (384 kcps vs. 546 kcps). The median and maximum wide-spectrum count rate for patients treated with [

conclusionsWhile high-quality

Indexed as

161TbCollimatorDead timeDosimetryGamma cameraSensitivitySeptal penetrationSPECTTb-161Terbium-161

Identifiers

PMID40866721
PMCPMC12390893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.