Evidence map›Paper›PMID 40866649›Full record

ArticleBulletin of experimental biology and medicine2025

Behavioral Characteristics of Female Rats on the Model of Pain Syndrome in the Maxillofacial Region.

A V Klimenko, D A Cheremisova, O S Romanenko, S S Pertsov

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A V KlimenkoFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia. klimenko_av@academpharm.ru.
D A CheremisovaFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia.
O S RomanenkoFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia.
S S PertsovFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in behavioral parameters in the open field and elevated plus maze tests were studied in female rats with experimental osteoarthritis of the temporomandibular joint (TMJ) caused by intra-articular injection of sodium monoiodoacetate (16 mg/kg). In the elevated plus maze, the animals with experimental pain syndrome demonstrated the following dynamics of behavioral parameters: the latency of leaving the central platform and the time spent in closed arms increased, while the number of visits to closed arms and numbers of head dips and rearings decreased on day 25 of the experiment in comparison with the baseline levels. In the open-field, the latency of the first movement and grooming time increased and the number of objects explored decreased by day 26. Changes in the behavior of rats with pain syndrome manifested in a pronounced inhibition of orientation and exploratory activity, increased anxiety, and suppression of motor activity and persisted for a long time after injection of sodium monoiodoacetate into TMJ.

Indexed as

Behavior, AnimalOsteoarthritisPainAnimalsAnxietyDisease Models, AnimalExploratory BehaviorFemaleInjections, Intra-ArticularIodoacetic AcidMaze LearningMotor ActivityRatsRats, WistarTemporomandibular JointIodoacetic Acidbehavior in open field and elevated plus mazeexperimental pain syndromefemale ratssodium monoiodoacetatetemporomandibular joint

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.