Evidence map›Paper›PMID 40866515›Full record

ArticleScientific reports2025

Low bone mineral density of the spine in adolescents with cerebral palsy relates to reduced correction of scoliosis after surgery.

Konstantinos Tsaknakis, Charlotte Scheulen, Katja A Lüders, Heide Siggelkow, Heiko M Lorenz, Lena Braunschweig, Anna K Hell

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos TsaknakisPaediatric Orthopaedics, Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen, Georg-August-University, 37075, Goettingen, Germany.ORCID http://orcid.org/0000-0002-7102-5892
Charlotte ScheulenPaediatric Orthopaedics, Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen, Georg-August-University, 37075, Goettingen, Germany.
Katja A LüdersPaediatric Orthopaedics, Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen, Georg-August-University, 37075, Goettingen, Germany.
Heide SiggelkowPaediatric Orthopaedics, Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen, Georg-August-University, 37075, Goettingen, Germany.
Heiko M LorenzPaediatric Orthopaedics, Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen, Georg-August-University, 37075, Goettingen, Germany.
Lena BraunschweigPaediatric Orthopaedics, Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen, Georg-August-University, 37075, Goettingen, Germany.
Anna K HellPaediatric Orthopaedics, Department of Trauma, Orthopaedic and Plastic Surgery, University Medical Center Goettingen, Georg-August-University, 37075, Goettingen, Germany. anna.hell@med.uni-goettingen.de.ORCID http://orcid.org/0000-0002-6655-7130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescents with cerebral palsy (CP) often require scoliosis surgery. Low bone mass may counteract benefits of surgical treatment. This study compares volumetric bone mineral density (vBMD) in adolescents with CP to age and sex matched healthy controls and evaluates its effect on scoliosis treatment. Computed tomogramms (CT) of 51 adolescents with CP (15.0 ± 2.6 years) were performed for scoliosis surgery and also used for vBMD calculation. Reference control vBMD values were calculated from 62 CT examinations of patients (15.1 ± 2.3 years) after trauma or conditions not related to bone mass. Z-scores were calculated based on the reference values. Correction of scoliosis in relation to vBMD was evaluated on perioperative spinal radiographs of operated adolescents with CP. Adolescents with CP had lower vBMD (123.3 ± 46.3 mg/cm

Indexed as

Bone DensityCerebral PalsyScoliosisSpineAdolescentCase-Control StudiesFemaleHumansMaleTomography, X-Ray ComputedAdolescentsBone mineral densityCerebral palsyOsteoporosisPathological FractureScoliosis

Identifiers

PMID40866515
PMCPMC12391410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.