Evidence map›Paper›PMID 40866456›Full record

ArticleScientific reports2025

Chemical profiling and biological assessment of essential oil from Artemisia herba-alba.

Odey Bsharat, Yousef Salama, Nisreen Al-Hajj, Eman Saed, Nidal Jaradat, Ismail Warad, Nawaf Al-Maharik

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Odey BsharatDepartment of Chemistry, Faculty of Sciences, An-Najah National University, P.O. Box. 7, Nablus, Palestine. obsharat@najah.edu.
Yousef SalamaAn-Najah Center for Cancer and Stem Cell Research, Faculty of Medicine, Allied Medical Sciences, An-Najah National University, P.O. Box 7, Nablus, 00970, Palestine.
Nisreen Al-HajjDepartment of Chemistry, Faculty of Sciences, An-Najah National University, P.O. Box. 7, Nablus, Palestine.
Eman SaedDepartment of Chemistry, Faculty of Sciences, An-Najah National University, P.O. Box. 7, Nablus, Palestine.
Nidal JaradatDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 00970, Palestine.
Ismail WaradDepartment of Chemistry, Faculty of Sciences, An-Najah National University, P.O. Box. 7, Nablus, Palestine.
Nawaf Al-MaharikDepartment of Chemistry, Faculty of Sciences, An-Najah National University, P.O. Box. 7, Nablus, Palestine. n.maharik@najah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, essential oils (EOs) have garnered attention for their biological properties as a source of natural compounds with anticancer and antioxidant effects. Artemisia herba alba grows commonly on the dry steppes of the Mediterranean regions in Northern Africa, Western Asia, and Southwestern Europe. This species is native to Palestine and the western region of Jordan, known as Sheeh. It is employed by the Bedouins for the remedy of many diseases. Recently, essential oils (EOs) have been booming with a growing interest in their use as palliative treatments to conventional medicine due to their biological qualities. The objective of this study is to identify the chemical composition of EO extracted from the dry leaves of A. herba alba and to evaluate their in vitro antioxidant, anticancer, and α-amylase and lipase inhibitory activity. The EO was extracted via hydrodistillation and examined using gas chromatography-mass (GC-MS) spectrometry to determine its chemical composition. The primary components included 1,8-cineole (28.67%), followed by trans-thujone (24.00%), cis-thujone (17.69%), camphor (12.76%), and concluding with terpinen-4-ol (8.34%). Biologically, the EO performed high antioxidant activity against 1,1-diphenyl-2-picrylhydrzyl (DPPH) with 22.17 ± 1.11 µg/mL and modest lipase and α-amylase activity. The EO displayed significant anticancer properties against B16F10 and MCF-7 with IC

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsArtemisiaOils, Volatilealpha-AmylasesAnimalsDrug SynergismGas Chromatography-Mass SpectrometryHumansInhibitory Concentration 50LipaseMCF-7 CellsMicePaclitaxelPlant Leavesalpha-AmylasesAntineoplastic Agents, PhytogenicAntioxidantsLipaseOils, VolatilePaclitaxelAnticancerAntioxidantArtemisia herba albaB16F10Chemical compositionEssential oilLipaseMCF-7α-amylase

Identifiers

PMID40866456
PMCPMC12391292

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